Association between Hyperuricemia and Ischemic Stroke: A Case-Control Study

Fatima, Tooba; Iftikhar, Sadaf; Qureshi, Irshad Hussain

doi:10.29271/jcpsp.2020.08.853

Cited by 5 publications

(4 citation statements)

References 11 publications

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“…Ghayyur et al noted an average age with SD of 60.47 ± 7.78 years, with a male-female ratio of 56.4% to 43.6% [ 17 ]. Further, Fatima et al found a mean age with SD of 60.82 ± 9.30 years, evenly split between 50% of males and females in their ischemic stroke patient cohort [ 18 ]. In contrast, Nasim et al reported a younger mean age with an SD of 51.2 ± 8.4 years, with a higher proportion of patients aged between 41 and 65 years and a male predominance (69.52%) in their study sample, indicating variations in age distribution and gender ratios across different studies [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Frequency of Hypomagnesemia and Its Relationship With Severity Among Patients of Acute Ischemic Stroke Presenting to a Tertiary Care Hospital

Khanum,

Arshad,

ullah

et al. 2024

Cureus

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The objective of this study was to assess the prevalence of hypomagnesemia and its association with the severity of acute ischemic stroke (AIS) in patients presenting at a tertiary care hospital. MethodologyA total of 100 patients with AIS were included in the study. Demographic data, including age, gender, and severity of stroke, were collected. Serum magnesium levels were measured at admission, and the severity of stroke was classified as mild, moderate, or severe based on clinical criteria. The presence of hypomagnesemia was defined as a serum magnesium level below 1.8 mg/dL determined within 72 hours of onset of stroke. Statistical analysis was performed to assess the association between hypomagnesemia, stroke severity, age, and gender. ResultsThe mean age of the patients with standard deviation was 65.45 ± 11.8 years, with the majority (38, 38%) aged 60-74 years. There were 53 (53%) male and 47 (47%) female patients. Hypomagnesemia was found in 35 (35%) patients, with an average magnesium level of 1.93 mg/dL and a standard deviation of 0.37 at admission. There was no statistically significant difference in the distribution of stroke severity (P = 0.779; P = 0.406) or hypomagnesemia (P = 0.287; P = 0.591) based on gender or age group, respectively. Stratification based on stroke severity showed that 16 (39%) patients with mild stroke, 10 (31.3%) with moderate stroke, and 9 (33.3%) with severe stroke had hypomagnesemia. The correlation between stroke severity and hypomagnesemia was weak (r = 0.099). Further, among hypomagnesemia patients, the majority were females aged 60-74 years. ConclusionsThis study found a weak positive relationship between the severity of AIS and the presence of hypomagnesemia. However, no statistically significant association was observed between gender or age group and stroke severity or hypomagnesemia. These findings suggest that further research is needed to understand the role of hypomagnesemia in AIS and its potential implications for patient management.

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Section: Discussionmentioning

confidence: 99%

Frequency of Hypomagnesemia and Its Relationship With Severity Among Patients of Acute Ischemic Stroke Presenting to a Tertiary Care Hospital

Khanum,

Arshad,

ullah

et al. 2024

Cureus

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“…Descriptive and analytical outcomes were calculated, utilizing different statistical techniques, which include percentages, frequencies, Chi-square and binary logistic regression model. To determine the p -value and to look for a relationship between migraine and risk factors, the Chi-Square test was used [ 37 ]. Since the variables in the QOL section are categorical and chi-square handles qualitative variables, we were utilized it there.…”

Section: Methodsmentioning

confidence: 99%

Association between risk factors and migraine in Pakistani females

Razzak,

Khan,

Tariq

et al. 2023

BMC Women's Health

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Background Migraine is a typical cripple issue of the brain identified with cerebral pain which is an indication of numerous health conditions. About 18% of women (27 million) and 6% of men (10 million) are afflicted by migraine in the United States. Based on a case-control study, to explore the different risk factors, causing migraine in females and examine the association between risk factors and migraine. Methods A sample of 1055 individuals were selected in different areas of Lahore from September 2019 to March 2020. The information was obtained by using the direct interview method and questionnaire method. Descriptive analysis, bivariate analysis and binary logistic regression analysis were carried out in data analysis. Results Among 1055 individuals 740 cases and 315 controls were included. In a binary logistic regression model, physical activities, stress, summer season, menstruation and morning were the risk factors that cause migraine and these were found to be positively significant with the odds ratios and 95% confidence interval of odds ratios (1.399; 1.122–1.746), (1.510; 1.187–1.922), (1.595; 1.374–1.851), (1.513; 1.247–1.836) and (1.309; 1.028–1.665) respectively. Nausea, isolation and back head pain were caused by migraine and these were found positively significant with the odds ratios and 95% confidence interval of odds ratios(1.290; 1.122–1.484), (1.882; 1.617–2.190) and (1.285; 1.123–1.471) respectively. Conclusions Stress, physical Activities and Menstruation increase the risk of migraine but weight loss, Breakfast, lunch, thirst, injury and Second trimester during pregnancy reduce the risk of migraine.

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“…Также подтверждена роль уровня МК в качестве маркера и/или предиктора сердечно-сосудистой смертности и долгосрочных нежелательных событий у пациентов с ИБС [45,46]. В ряде работ продемонстрирована связь гиперурикемии с коронарным атеросклерозом, атеросклеротическим поражением брахиоцефальных артерий, преэклампсией, инсультом и сосудистой деменцией [47][48][49][50].…”

Section: Uric Acid As a Risk Factor For Cardiovascular Diseases мочев...unclassified

Uric Acid as a Risk Factor for Cardiovascular Diseases

Safaryan¹,

Лишута

Небиеридзе³

2022

Racionalʹnaâ farmakoterapiâ v kardiologii

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Recently, hyperuricemia and its association with cardiovascular disease have been receiving more and more attention. The article talks about the role of uric acid in the body, the reasons for its increase and the impact of elevated uric acid levels on the cardiovascular system. The mechanisms of influence of hyperuricemia on the development and progression of cardiovascular diseases are presented. Medicinal and non-drug ways to reduce the level of uric acid in the blood are considered. From non-drug methods, attention is focused on the hypopurine diet, adequate drinking regimen and normalization of body weight. Separately, the effect on the level of uric acid of various drugs used in clinical practice is considered. In the light of current clinical guidelines, the issue of the need to prescribe drug therapy for asymptomatic hyperuricemia is discussed.

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Association between Hyperuricemia and Ischemic Stroke: A Case-Control Study

Abstract: Objective: To find the association between hyperuricemia and ischemic stroke. Study Design: Case-control study.

Cited by 5 publications

References 11 publications

Frequency of Hypomagnesemia and Its Relationship With Severity Among Patients of Acute Ischemic Stroke Presenting to a Tertiary Care Hospital

Frequency of Hypomagnesemia and Its Relationship With Severity Among Patients of Acute Ischemic Stroke Presenting to a Tertiary Care Hospital

Association between risk factors and migraine in Pakistani females

Uric Acid as a Risk Factor for Cardiovascular Diseases

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