Association between STAT4 gene polymorphism and susceptibility to pulmonary tuberculosis in the Moldavian population
Alexander Varzari,
Elena Tudor,
Andrei Corloteanu
et al.
Abstract:Signal transducer and activator of transcription 4 (STAT4) plays a crucial role in the host immune response against Mycobacterium tuberculosis. This study investigates the association between STAT4 gene polymorphisms and pulmonary tuberculosis (TB) risk in the Moldavian population. A total of 272 TB patients and 251 community‐matched controls underwent screening for functional single‐nucleotide polymorphisms (SNPs) rs897200 and rs7574865 in the STAT4 gene. The minor T allele and the TT/CT genotype of rs897200 … Show more
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