Association between Initial Treatment Strategy and Long-Term Survival in Pulmonary Arterial Hypertension

Abstract

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Carbon Monoxide Diffusion Capacity as a Severity Marker in Pulmonary Hypertension

“…Other non-invasive parameters are also eligible for the assessment of prognosis in PH as shown for echocardiography [ 44 ]. As risk stratification has been recently shown to be critical in the initial choice of treatment, we think that any further improvement in prognosis prediction deserves consideration [ 45 ].…”

Upfront Combination Therapy for Pulmonary Arterial Hypertension: Time to Be More Ambitious than AMBITION

“…In this context, in this issue of the Journal , Boucly and colleagues (pp. 842–854 ) present a retrospective cohort study evaluating the association between initial treatment strategy and survival among patients with newly diagnosed PAH using the French PH Registry ( 4 ). The study included 1,611 patients, of whom 984, 551, and 76 were treated with an initial strategy of mono, dual, or triple therapy with a parenteral prostacyclin and were followed for a median of 32 months.…”

Hit Early and Hit Hard in Pulmonary Arterial Hypertension? Not So Fast!

“…In this issue of the Journal , Boucly and colleagues (pp. 842–854 ) examined, in this context, the impact of initial treatment strategy on long-term survival in PAH ( 7 ). The study consisted of a retrospective analysis of 1,611 patients with incident idiopathic, heritable, or anorexigen-induced PAH.…”