Association between lean body mass and hypertension: A cross‐sectional study of 50 159 NHANES participants

Abstract

Increasing attention has been paid to the association between lean body mass (LBM) and hypertension in recent years, but the previous findings have often been contradictory. Therefore, the authors investigated the association between LBM and hypertension through a cross‐sectional study in the United States. To investigate the relationship between LBM and hypertension, the authors conducted weighted multivariable logistic regression models. The authors used the restricted cubic spline regression model to determine if there was a nonlinear correlation. In order to locate the inflection point, the authors built a two‐part linear regression model using a recursive method. In the full adjustment model, LBM was positively associated with hypertension, with ORs (95% CI) of 1.19 (1.02, 1.38). In the further linear trend test, the ORs (95% CI) for Q2, Q3, and Q4 were 0.76 (0.60, 0.95), 0.62 (0.47, 0.80), and 0.66 (0.48, 0.91), respectively, compared to Q1, which suggested that the association between LBM and hypertension might be non‐linear. The authors performed the restricted cubic spline curve to confirm this non‐linear relationship and found the inflection point of 43.21 kg with an opposite relationship in which LBM and hypertension exhibited a negative correction of 0.66 (0.50, 0.86) before the inflection point and a positive correlation of 1.20 (1.03, 1.39) after the inflection point. Our study highlighted a non‐linear association between LBM and hypertension in the general US population.

Association between red cell distribution width and hypertension: Results from NHANES 1999–2018

“…The blood pressure measurements of participants from 2017 to 2018 were conducted using the digital upper arm electronic measurement device Omron HEM-907XL, with three consecutive blood pressure measurements taken at 60 second intervals. Based on 2018 ESC/ESH Guidelines for the management of arterial hypertension [ 16 ] and recent literature on hypertension in NHANES, this study used four data sources to evaluate hypertension [ 17 , 18 ]. The first one is based on the questionnaire "Have you ever been informed by a doctor or other health professional that you have hypertension, also known as hypertension?…”