2024
DOI: 10.1177/10781552241252374
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Association between plasma imatinib levels and response to treatment of chronic myeloid leukemia in patients from Manaus, Brazil

Maíra Araújo Henriques,
Frank do Carmo Guedes Júnior,
Lílian Minako Karube
et al.

Abstract: Introduction Imatinib mesylate (IM) is the drug of choice for the treatment of chronic myeloid leukemia (CML). However, despite most of the results obtained with this therapy being positive, some patients still present a suboptimal therapeutic response or still develop some type of resistance. Therefore, the aim of this study was to evaluate IM plasma levels in CML patients treated at a referral unit in Manaus and correlate them with variables that might interfere with these levels. Methods Data from 52 patien… Show more

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