Association Between Post-Operative Infection and Blood Transfusion in Cardiac Surgery

Abukhodair, Abdulkarim W; Alqarni, Mohammed S; Bukhari, Ziad M.; Qadi, Ammar; Mufti, Hani N.; Fernández, José A.; Bennett, Sean

doi:10.7759/cureus.8985

Cited by 4 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The blood consumption of cardiac surgery accounts for a large proportion of the total blood consumption, up to more than 60%, and ranks first in surgical blood consumption. 24 It is much more obvious in patients with aortic dissection than other cardiac surgeries owing to the preoperative thrombosis, consumption of platelets and other coagulation factors, complexity of surgery, and longer CPB time than other cardiac surgery. Therefore, massive hemorrhage and blood transfusion in the perioperative period are also difficult problems for cardiac surgeons.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Prognosis and Risk Factors for Postoperative Hepatic Dysfunction in Patients with Acute Type A Aortic Dissection

Wei¹

2023

Anatol J Cardiol

View full text Add to dashboard Cite

Background: To explore the prognosis and risk factors of postoperative hepatic dysfunction in patients with acute type A aortic dissection. Methods: A total of 156 patients who underwent surgery for acute type A aortic dissection in our hospital from May 2014 to May 2018 were retrospectively enrolled. The patients were divided into 2 groups based on postoperative liver function. The postoperative model for end-stage liver disease score was used to define hepatic dysfunction. There were 35 patients with postoperative hepatic dysfunction (group hepatic dysfunction, model for end-stage liver disease score ≥ 15) and 121 patients without postoperative hepatic dysfunction (group non-hepatic dysfunction, model for end-stage liver disease score < 15). Univariate and multiple analyses (logistic regression) were used to identify the predictive risk factors. Results: In-hospital mortality rate was 8.3%. Multiple logistic analysis showed that preoperative alanine aminotransferase ( P < .001), cardiopulmonary bypass time ( P < .001), and red blood cell transfusion ( P < .001) were independent determinants for postoperative hepatic dysfunction. The patients were followed up for 2 years, with an average follow-up of 22.9 ± 3.2 months, and the lost follow-up rate was 9.1%. The short- and medium-term mortality in hepatic dysfunction group was higher than that in non-hepatic dysfunction group (log-rank P = .009). Conclusions: The incidence of postoperative hepatic dysfunction is high in patients with acute type A aortic dissection. Preoperative alanine aminotransferase, cardiopulmonary bypass time, and red blood cell transfusion were independent risk factors for those patients. The short- and medium-term mortality in hepatic dysfunction group was higher than that in non-hepatic dysfunction group.

show abstract

Section: Discussionmentioning

confidence: 99%

Analysis of Prognosis and Risk Factors for Postoperative Hepatic Dysfunction in Patients with Acute Type A Aortic Dissection

Wei¹

2023

Anatol J Cardiol

View full text Add to dashboard Cite

show abstract

“…38 According to recent studies, more conservative blood transfusion protocols are being used in various centers. 39 Postoperative Infection has been reported the associated controversial risk with blood transfusion. 40 It has been reported that preoperative anemia, morbidity, mortality, and higher hospital costs are associated with increased blood transfusions.…”

Section: A H E a D O F P R I N Tmentioning

confidence: 99%

Modifiable Risk Factors associated with Post-Operative Bleeding and transfusion requirements in Cardiac Surgery

Khan¹,

Islam²,

Ahmad³

et al. 2022

Pak J Med Sci

View full text Add to dashboard Cite

Objectives: In this study we determine the modifiable factors related to bleeding and transfusion in post-cardiac surgery patients who underwent open heart surgery. Methods: This is a retrospective study that include two hundred patients who had undergone open heart surgery (OHS) at Northwest General Hospital and Research Center from December 2018 to July 2021. Platelet count and hemoglobin level were measured in the pre-operative period. Results: This study included both male and female patients. Postoperative platelets were counted as follow: 50-100 x109 L in 3.0% cases, 101-150 x109 L seen in 27.5% cases, and >150 x 109 L in 69.5% cases which required transfusion. We have also reported the increased requirement of transfusion of blood and blood products in patients with pre-operative hemoglobin (Hb) < 10 g/dl. Conclusion: Correction of pre-op Hb, post-op platelet count and total bypass time are the significant and preventable parameters in patients undergoing cardiac surgery if proper pre-op assessment of the patient is performed. doi: https://doi.org/10.12669/pjms.38.4.5685 How to cite this:Khan B, Mujahid Ul Islam, Ahmad I, Mujeeb Ur Rehman. Modifiable Risk Factors associated with Post-Operative Bleeding and transfusion requirements in Cardiac Surgery. Pak J Med Sci. 2022;38(4):---------. doi: https://doi.org/10.12669/pjms.38.4.5685 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

show abstract

“…The identification of these factors is critical to reduce postoperative infections and to establish a special protocol for managing high-risk patients. At the King Faisal Cardiac Center, the rate of postoperative infection has been reported to be 32%, which is extremely high [ 14 ]. In light of this, the aim of this study was to determine the common risk factor related to postoperative infections among patients at the King Faisal Cardiac Center from January 2014 to September 2020.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Postoperative Infections in Cardiac Surgery Patients: A Retrospective Study

Abukhodair,

Alqarni,

Alzahrani

et al. 2023

Cureus

Self Cite

View full text Add to dashboard Cite

Background and objective Cardiac surgery is one of the most common surgical procedures globally; its incidence has been on the rise due to the faster pace of population aging thanks to technological and epidemiological advances. Patients who undergo cardiac surgeries may face various postoperative complications that might affect their survival, and one of these major complications is infection. Nosocomial pneumonia, surgical site infection (SSI), mediastinitis, bacteremia, and sepsis are common infections encountered after surgeries. In this study, we aimed to determine the common risk factors related to postoperative infections at the King Faisal Cardiac Center from January 2014 to September 2020. Materials and methods Records from 364 patients who underwent cardiac surgery and were aged above 18 years were assessed for postoperative infections in this retrospective cohort study. Patients who were immunosuppressed or had active systemic infections were excluded. Consent was waived by the Institutional Review Board. All procedures were performed at the King Faisal Cardiac Center, National Guard Hospital, Jeddah. Results Of the total 364 patients, 105 were women and 259 were men. The mean age of the cohort was 59 years (SD = 13) and the mean BMI was 29.1 kg/m 2 (SD = 5.3). The study population showed a high prevalence of cardiac risk factors and diseases: diabetes (n = 244, 67%), hypertension (n = 230, 63%), dyslipidemia (n = 144, 40%), smoking (n = 80, 22%), heart failure (n = 41, 11%), and chronic obstructive pulmonary disease (n = 6, 1.6%). The overall rate of postoperative infection was 32.7% (n = 120), and 17 (14%) of these infected patients underwent reoperations for infection. Conclusion Based on a thorough analysis of 364 patients undergoing various cardiac surgical procedures, including a multivariate analysis accounting for preoperative factors, there was a significant association between postoperative infections and hypertension, diabetes, increased preoperative activated partial thromboplastin time, and elevated HbA1c.

show abstract

Association Between Post-Operative Infection and Blood Transfusion in Cardiac Surgery

Cited by 4 publications

References 21 publications

Analysis of Prognosis and Risk Factors for Postoperative Hepatic Dysfunction in Patients with Acute Type A Aortic Dissection

Analysis of Prognosis and Risk Factors for Postoperative Hepatic Dysfunction in Patients with Acute Type A Aortic Dissection

Modifiable Risk Factors associated with Post-Operative Bleeding and transfusion requirements in Cardiac Surgery

Risk Factors for Postoperative Infections in Cardiac Surgery Patients: A Retrospective Study

Contact Info

Product

Resources

About