Association between serum vitamin B12 levels and frailty in older adults

Dokuzlar, Özge; Soysal, Pınar; Işık, Ahmet Turan

doi:10.14744/nci.2017.82787

Cited by 15 publications

(24 citation statements)

References 23 publications

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“…22 In a study carried out in Turkey, the prevalence of frailty was found to be 26.3% in individuals aged >65 years. 12 Similarly, the prevalence of frailty in the present study was 25.7%. It is known that frailty is more common in women.…”

Section: Discussionsupporting

confidence: 69%

“…Although the prevalence of frailty varies according to the scales used, it is between 7% and 12% among individuals aged >65 years . In a study carried out in Turkey, the prevalence of frailty was found to be 26.3% in individuals aged >65 years . Similarly, the prevalence of frailty in the present study was 25.7%.…”

Section: Discussionsupporting

confidence: 53%

“…In all analyses, P < 0.05 was considered to show statistical significance. A sample size of 272 participants was calculated to ensure that the minimum required size was within a 95% confidence interval and 5% standard error, based on a previous study that reported the prevalence of frailty was 26.3% …”

Section: Discussionmentioning

confidence: 99%

“…Any question in favor of dependency and frailty is considered as a score in the KCL, and indicates that the individual is at a high risk of requiring support or care in the relevant field . The prevalence of frail and prefrail older adults in Turkey is high . Therefore, easy‐to‐apply frailty scales are required for early detection of these patients.…”

Section: Introductionmentioning

confidence: 99%

“…7 The prevalence of frail and prefrail older adults in Turkey is high. 11,12 Therefore, easy-to-apply frailty scales are required for early detection of these patients. The aim of the present study was to test the validity of a Turkish version of the KCL, and to evaluate its strength in determining the frailty defined by Fried criteria.…”

Section: Introductionmentioning

confidence: 99%

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Validity of the Kihon Checklist for evaluating frailty status in Turkish older adults

Esenkaya

Dokuzlar

Soysal

et al. 2019

Geriatrics Gerontology Int

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Aim The Kihon Checklist (KCL) was developed to identify vulnerable older adults residing in Japan who are at a high risk of becoming dependent. The present study aimed to determine the validity of the KCL for detecting frailty in Turkish older adults. Methods A total of 300 outpatients were enrolled in the study. All patients underwent comprehensive geriatric assessment and completed a Turkish translation of the KCL. Frailty status was defined by five dimensions, including weight loss, exhaustion, low levels of activity, weakness and slowness: 0 for robust, 1–2 for prefrail and 3–5 for frail. Results The mean age of the patients was 73.85 ± 7.12 years. According to Fried definitions, 25.7% were considered frail, 48.0% prefrail and 26.3% robust. There was a significant difference between the groups in terms of age, sex, education, Charlson's Comorbidity Index, the number of medications used, sarcopenia, dynapenia and all the comprehensive geriatric assessment parameters (P < 0.05). Cronbach's α value of the KCL was 0.876. The area under the receiver operating characteristics curve was 0.855 for frail, and 0.697 for prefrail. We found that the KCL can show frail and prefrail older adults when the cut‐off values are ≥9 and ≥ 4, respectively, with a sensitivity of 80.52% and 65.28%, and specificity of 81.17% and 56.96%. Conclusions The KCL can be used as a quick, simple and sensitive screening method for detecting frailty among Turkish older adults. We recommend its use by healthcare professionals in Turkey in order to identify frail older adults and direct them to relevant support. Geriatr Gerontol Int 2019; 19: 616–621.

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Section: Discussionsupporting

confidence: 69%

Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Validity of the Kihon Checklist for evaluating frailty status in Turkish older adults

Esenkaya

Dokuzlar

Soysal

et al. 2019

Geriatrics Gerontology Int

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How gait influences frailty models and health‐related outcomes in clinical‐based and population‐based studies: a systematic review

Bortone

Sardone

Lampignano

et al. 2021

J cachexia sarcopenia muscle

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Aging is often associated with a decline in physical function that eventually leads to loss of autonomy in activities of daily living (ADL). Walking is a very common ADL, important for main determinants of quality of life in older age, and it requires the integration of many physiological systems. Gait speed has been described as the 'sixth vital sign' because it is a core indicator of health and function in aging and disease. We reviewed original studies up to June 2020 that assessed frailty in both longitudinal and cross-sectional observational studies, paying particular attention to how gait is measured in older population and how the gait parameter adopted may influence the estimated frailty models and the health-related outcomes of the various studies (i.e. clinical, cognitive, physical, and nutritional outcomes). Eighty-five studies met the search strategy and were included in the present systematic review. According to the frailty tools, more than 60% of the studies used the physical phenotype model proposed by Fried and colleagues, while one-third referred to multi-domain indexes or models and only 5% referred to other single-domain frailty models (social or cognitive). The great heterogeneity observed in gait measurements and protocols limited the possibility to directly compare the results of the studies and it could represent an important issue causing variability in the different outcome measures in both clinical-and population-based settings. Gait appeared to be an indicator of health and function also in frail older adults, and different gait parameters appeared to predict adverse health-related outcomes in clinical, cognitive, and physical domains and, to a lesser extent, in nutritional domain. Gait has the potential to elucidate the common basic mechanisms of cognitive and motor decline. Advances in technology may extend the validity of gait in different clinical settings also in frail older adults, and technology-based assessment should be encouraged. Combining various gait parameters may enhance frailty prediction and classification of different frailty phenotypes.

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Developing and validating an electronic health record-based frailty index in pre-operative settings using machine learning

Bai,

Al-Ani,

Amini

et al. 2023

J Intell Inf Syst

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Association between serum vitamin B12 levels and frailty in older adults

Cited by 15 publications

References 23 publications

Validity of the Kihon Checklist for evaluating frailty status in Turkish older adults

Validity of the Kihon Checklist for evaluating frailty status in Turkish older adults

How gait influences frailty models and health‐related outcomes in clinical‐based and population‐based studies: a systematic review

Developing and validating an electronic health record-based frailty index in pre-operative settings using machine learning

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