Association between SOX5 Genotypes and Semen Quality in Polish Holstein-Friesian Bulls

Hering, Dorota; Kamiński, Stanisław

doi:10.1515/pjvs-2016-0082

Cited by 3 publications

(1 citation statement)

References 7 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In yak and cattleyak studies, downregulation of the bta-let-7 family, bta-miR-125, and bta-miR-23a may impair RA-induced sperm division (10). The target mRNA ENSBTAG000000022360 of circRNA 5:86629598|86690338 corresponds to the gene SOX5 associated with Polish Holstein-Friesian Bulls' semen quality (45), so there may be a 5:86629598|86690338 to bta-let-7b to SOX5 relationship chain in this study. Bta-mir-103 may be related to heat stress (46) and sperm motility (47) after cryopreservation in cattle and the expression of bta-mir-103 in yak and cattleyak testis is also different (10).…”

Section: Discussionmentioning

confidence: 99%

Identification and analysis of differentially expressed (DE) circRNA in epididymis of yak and cattleyak

Yan²,

Pan³

et al. 2023

Front. Vet. Sci.

View full text Add to dashboard Cite

Circular RNAs (circRNAs), as endogenous non-coding RNA with unique closed ring structure, is closely related to animal reproduction, and understanding the expression of circRNA in yak and cattleyak epididymal tissues is of great significance for understanding cattleyak sterility. Based on this, we screened and identified the differentially expressed circRNA in the epididymis of three yaks and two cattleyak. A total of 1,298 circRNAs were identified in the epididymis of yak and cattleyak, of which 137 differentially expressed (DE) circRNAs and the functions of some of them were elucidated in this research, as well as qPCR verification to 6 circRNAs from the 137 DE circRNAs. Gene Ontology (GO) enrichment analysis suggested that DE circRNAs were mainly related to metabolic process, development process, immune system process, reproductive process, reproduction, biological adhesion and growth. COG classification analysis showed that the DE circRNAs derived genes were mainly related to replication, recombination and repair. KEGG pathway analysis suggested that DE circRNAs were mainly involved in RNA degradation. In addition, we also screened Bta-mir-103, which is a circRNA binding miRNA related to sperm activity.

show abstract