Association between the oxidative balance score and low muscle mass in middle-aged US adults

Chen, Kun; Yin, Qiang; Guan, Jiangan; Yang, Jingwen; Ma, Yuan; Hu, Yu; Chen, Chan; Chen, Wenwen

doi:10.3389/fnut.2024.1358231

Cited by 3 publications

References 64 publications

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Association between oxidative balance score and endometriosis findings from NHANES 1999–2006

SU,

Du,

Liu

et al. 2024

Preprint

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Aim The Oxidative Balance Score (OBS) functions as a measure for gauging the oxidative stress condition, OBS has been utilized to assess the overall oxidants and antioxidants exposure status in various chronic disease studies, Growing evidence suggests that oxidative stress is involved in the pathophysiologic mechanisms of endometriosis, The purpose of this study was to investigate the association between OBS and endometriosis in women between the ages of 20 and 54. Methods and Results The correlation between OBS and endometriosis was meticulously examined through a multifaceted approach, encompassing multivariate logistic regression, sensitivity analysis, and the application of smoothing techniques for curve fitting. This analysis was conducted utilizing the extensive dataset from the National Health and Nutrition Examination Survey (NHANES) spanning the years 1999 to 2006. To ascertain the stability of the observed relationship across diverse demographic segments, subgroup analysis, and interaction tests were meticulously implemented. Among the 3881 participants aged between 20 and 54 years, a significant inverse association was identified between OBS scores and the presence of endometriosis. Specifically, within the comprehensively adjusted model, for every 1 score increase in OBS, the odds of endometriosis prevalence decreased by 2.00%. The highest quartile of OBS demonstrated a 29.1% reduction in the prevalence of endometriosis when compared to those in the lowest quartile, with a confidence interval of [0.480, 1.048], underscoring the robustness of the observed trend. Conclusions OBS is related to endometriosis among American adults. Our results suggest that elevated OBS may potentially reduce the odds of endometriosis prevalence.

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Association between oxidative balance score and endometriosis findings from NHANES 1999–2006

SU,

Du,

Liu

et al. 2024

Preprint

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The relationship between oxidative balance score and circadian syndrome: evidence from the NHANES 2005-2018

Xie,

Li,

et al. 2024

Front. Endocrinol.

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BackgroundThe oxidative balance score (OBS) is a composite indicator that evaluates the balance between pro-oxidants and antioxidants in one’s diet and lifestyle. However, the relationship between OBS and circadian syndrome (CircS) has remained unexplored. This investigation aimed to determine a correlation between OBS and CircS.MethodsThis population-based study examined 7,202 participants from the 2005 to 2018 National Health and Nutrition Examination Survey (NHANES), 1,433 of whom had CircS. We utilized weighted multivariate logistic regression, trend tests, subgroup analysis, and interaction tests to evaluate the correlation between OBS (total OBS, dietary OBS, and lifestyle OBS) and CircS. Restricted cubic splines (RCS) models and threshold effect analysis were used to explore nonlinear relationships.ResultsMultivariate logistic regression analysis indicated that the protective factor for CircS was a high OBS level (total OBS: Odds ratio (OR) = 0.95, 95% Confidence interval (CI): 0.93-0.97; dietary OBS: OR = 0.98, 95% CI: 0.96-1.00; lifestyle OBS: OR = 0.65, 95% CI: 0.61-0.69). Compared to the quartile 1 group, OBS (total OBS, dietary OBS, and lifestyle OBS) was negatively and statistically significantly associated with the risk of developing Circs in the quartile 4 group (total OBS: OR = 0.47, 95% CI: 0.32-0.70; dietary OBS: OR = 0.69, 95% CI: 0.48-0.99; lifestyle OBS: OR = 0.07, 95% CI: 0.04-0.11). According to subgroup analysis and interaction tests, there was an interaction effect between the association of lifestyle OBS and CircS in terms of education level (p for interaction = 0.01). Furthermore, we observed a nonlinear negative relationship between lifestyle OBS and CircS prevalence, with inflection points at 6 (p for nonlinearity = 0.002).ConclusionThe results showed a substantial negative connection between OBS and CircS. Encouraging foods filled with antioxidants and antioxidant-rich lifestyles may reduce the risk of CircS.

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Association between oxidative balance score and serum cobalt level in population with metal implants: a cross-sectional study from NHANES 2015–2020

Yuan,

Chen,

Sun

et al. 2024

Front. Nutr.

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BackgroundGrowing evidence indicates that metal implants influence the body’s oxidative stress status, which in turn affects the degradation and stability of metal implants. The oxidative balance score (OBS) is a composite indicator, reflecting the overall oxidative balance of pro-and antioxidants of the human body. However, the associations between OBS and the level of metal ions on the population with metal implants remain to be elucidated.MethodsWe conducted a cross-sectional study using data from 2015 to 2020 National Health and Nutrition Examination Survey (NHANES). Dietary and lifestyle factors closely associated with oxidative stress were quantified to calculate the OBS. Weighted multivariate logistic regression and smooth curve fittings were performed to examine the relationship between OBS and serum cobalt levels. Subgroup analyses were stratified by age and gender. In cases where non-linearity was detected, threshold effects were assessed using a two-piecewise linear regression model.ResultsA total of 549 participants were included in this analysis. The dietary OBS was negatively associated with serum cobalt level in fully adjusted model (β = −0.179, 95%CI: −0.358 to −0.001, P: 0.04918). Stratified by age and gender, negative correlation of OBS and dietary OBS with serum cobalt level was observed only in men and age over 70 years participants. Threshold effect analysis showed linear relationships between OBS, dietary OBS and cobalt level in males. There were non-linear relationships between OBS, dietary OBS and cobalt level in age over 70 years participants, with inflection points identified at 16.3 and 8.7 for OBS and dietary OBS, respectively.ConclusionOur study confirms the inverse relationships between oxidative stress and serum cobalt level in individuals with metal implants, highlighting the significance of optimizing OBS to mitigate the risk of metal ion toxicity. These findings emphasize the importance of maintaining an antioxidant diet and lifestyle, particularly as they offer greater protective effect for males and the elderly population.

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Association between the oxidative balance score and low muscle mass in middle-aged US adults

Cited by 3 publications

References 64 publications

Association between oxidative balance score and endometriosis findings from NHANES 1999–2006

Association between oxidative balance score and endometriosis findings from NHANES 1999–2006

The relationship between oxidative balance score and circadian syndrome: evidence from the NHANES 2005-2018

Association between oxidative balance score and serum cobalt level in population with metal implants: a cross-sectional study from NHANES 2015–2020

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