Association between thyroid profile and serum bilirubin levels in term neonates on day 3 of life

Abstract

Background: The present study was conducted to correlate thyroid profile and serum bilirubin levels assessed in term neonates on day 3 of life. Materials & Methods: The present study was conducted on146 neonate's ≥37 weeks of gestational age of both genders. Birth weight, gestational age, thyroid profile (T3, T4, TSH), serum bilirubin level (SBR) was calculated. Results: The mean gestational age was 272.4 days, birth weight was 2.8 Kgs, total bilirubin was 11.35 mg/dl, direct bilirubin was 0.46 mg/dl, fT3 level was 8.24 pg/ml, fT4 was 2.18 ng/dl and TSH was 4.08 mlU/ml. Normal expected neonates had normal T3, T4, TSH, TSB and direct Bilirubin level whereas 4 neonates had T3 level that ranged from 94-109, T4 from 5.8-8.2, TSH from 11.2-13.94, TSB from 10.2-16.2 and direct bilirubin from 0.31-0.54. Conclusion:Authors found no significant association between serum TSH and SBRT in term neonates.