Association between two distinct executive tasks in schizophrenia: a functional transcranial Doppler sonography study

Feldmann, Deborah; Schuepbach, Daniel; Rickenbach, Bettina von; Theodoridou, Anastasia; Hell, Daniel

doi:10.1186/1471-244x-6-25

Cited by 19 publications

(15 citation statements)

References 46 publications

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“…These studies were validated through direct comparison against the Wada test, which uses an anesthetic for lateral suspension of brain activity (Strauss et al 1985), and against fMRI establishing fTCD as a viable complementary tool for functional brain imaging (Binder et al 1996;Deppe et al 2000;Desmond et al 1995;Knecht et al 1998). Functional TCD has since been applied to the study of migraines (De Benedittis et al 1999;Backer et al 2001), stroke recovery (Bragoni et al 2000;Matteis et al 2003), Alzheimer's disease (Asil and Uzuner 2005), Parkinson's disease (Troisi et al 2002), Huntington's disease (Deckel and Cohen 2000) and schizophrenia (Sabri et al 2003;Feldmann et al 2006). …”

Section: Introductionmentioning

confidence: 99%

Functional Tissue Pulsatility Imaging of the Brain During Visual Stimulation

Kucewicz

Dunmire

Leotta

et al. 2007

Ultrasound in Medicine & Biology

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Functional tissue pulsatility imaging (fTPI) is a new ultrasonic technique being developed to map brain function by measuring changes in tissue pulsatility due to changes in blood flow with neuronal activation. The technique is based in principle on plethysmography, an older, non-ultrasound technology for measuring expansion of a whole limb or body part due to perfusion. Perfused tissue expands by a fraction of a percent early in each cardiac cycle when arterial inflow exceeds venous outflow and relaxes later in the cardiac cycle when venous drainage dominates. Tissue pulsatility imaging (TPI) uses tissue Doppler signal processing methods to measure this pulsatile "plethysmographic" signal from hundreds or thousands of sample volumes in an ultrasound image plane. A feasibility study was conducted to determine if TPI could be used to detect regional brain activation during a visual contrast-reversing checkerboard block paradigm study. During a study, ultrasound data were collected transcranially from the occipital lobe as a subject viewed alternating blocks of a reversing checkerboard (stimulus condition) and a static, gray screen (control condition). Multivariate Analysis of Variance (MANOVA) was used to identify sample volumes with significantly different pulsatility waveforms during the control and stimulus blocks. In 7 out 14 studies, consistent regions of activation were detected from tissue around the major vessels perfusing the visual cortex.

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Section: Introductionmentioning

confidence: 99%

Functional Tissue Pulsatility Imaging of the Brain During Visual Stimulation

Kucewicz

Dunmire

Leotta

et al. 2007

Ultrasound in Medicine & Biology

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“…Имеются работы, в которых проводились обследование пациентов с дислексией [48], эпилепсией [26,49,50], шизофренией [35,51,52], изучение внимания у пациентов с наличием и отсут-ствием артериальной гипертензии [53], у пожилых пациен-тов с признаками и без признаков депрессии [54], управля-ющих функций у пациентов с болезнью Гентингтона [55], ментальной активности у здоровых и пациентов в восстано-вительном периоде после инсульта [56][57][58]. В этих работах в зависимости от нозологии ставились разные цели.…”

Section: о б з о р ыunclassified

“…В ряде исследо-ваний не обнаружено различий в изменении СК при сопос-тавлении результатов у пациентов с той или иной патологи-ей и здоровых. Исключения в виде снижения СК были вы-явлены у больных шизофренией [51], депрессией [54] болез-нью Гентингтона [55] по сравнению со здоровыми. Напро-тив, у детей с серповидно-клеточной анемией при плохом выполнении когнитивных заданий наблюдалась аномально высокая СК [59].…”

Section: о б з о р ыunclassified

Transcranial Doppler Ultrasound Study of Brain Hemispheric Functional Specialization: A Review of Foreign Literature

Микадзе

Bogdanova

Лысенко

et al. 2016

RJTAO

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Изучение функциональной специализации полуша-рий и межполушарной асимметрии является предметом ис-следований в ряде нейронаук. Особый интерес представля-ет нейрокогнитивный подход, при использовании которого ставится задача описания структурно-функциональной ор-ганизации разных видов психической деятельности и вери-фикации ее психологической структуры и мозговой основы с помощью нейропсихологических и нейровизуализирую-щих методов [1]. Нейрокогнитивный подход, по словам Л. Сквайра, позволяет устанавливать важные связи между когнитивной психологией и неврологией [2].Для определения активности различных центров моз-га, отражающей переработку информации, используются электроэнцефалография (ЭЭГ) и различные нейровизуали-зирующие методы (функциональная магнитно-резонансная томография -фМРТ, позитронно-эмиссионная томо-графия -ПЭТ и др.), которые наряду с достоинствами име-ют определенные ограничения и недостатки, разные сте-пень сложности обслуживания и стоимость использования.Функциональная транскраниальная ультразвуковая допплерография (ФТКУЗДГ) -сравнительно недорогой, неинвазивный и безболезненный метод оценки скорости кровотока (СК). ФТКУЗДГ обеспечивает высокое времен-ное разрешение, гораздо более высокое, чем, например, фМРТ. При ее проведении пациент не должен оставаться неподвижным, наличие металлических имплантатов, татуи-ровок не влияет на результаты исследования, метод являет-ся щадящим для людей, страдающих клаустрофобией.

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“…The SOC has been described elsewhere in detail [17,18]. Briefly, the SOC was displayed on a touch-screen monitor that was divided into an upper part (goal state) and a lower part (start state), each containing three pockets (stockings) of different sizes.…”

Section: Methodsmentioning

confidence: 99%

Gender and Rapid Alterations of Hemispheric Dominance during Planning

Schuepbach¹,

Skotchko²,

Duschek³

et al. 2012

Neuropsychobiology

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Background: Mental planning and carrying out a plan provoke specific cerebral hemodynamic responses. Gender aspects of hemispheric laterality using rapid cerebral hemodynamics have not been reported. Method: Here, we applied functional transcranial Doppler sonography to examine lateralization of cerebral hemodynamics of the middle cerebral arteries of 28 subjects (14 women and 14 men) performing a standard planning task. There were easy and difficult problems, and mental planning without motor activity was separated from movement execution. Results: Difficult mental planning elicited lateralization to the right hemisphere after 2 or more seconds, a feature that was not observed during movement execution. In females, there was a dominance to the left hemisphere during movement execution. Optimized problem solving yielded an increased laterality change to the right during mental planning. Conclusions: Gender-related hemispheric dominance appears to be condition-dependent, and change of laterality to the right may play a role in optimized performance. Results are of relevance when considering laterality from a perspective of performance enhancement of higher cognitive functions, and also of psychiatric disorders with cognitive dysfunctions and abnormal lateralization patterns such as schizophrenia.

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Association between two distinct executive tasks in schizophrenia: a functional transcranial Doppler sonography study

Cited by 19 publications

References 46 publications

Functional Tissue Pulsatility Imaging of the Brain During Visual Stimulation

Functional Tissue Pulsatility Imaging of the Brain During Visual Stimulation

Transcranial Doppler Ultrasound Study of Brain Hemispheric Functional Specialization: A Review of Foreign Literature

Gender and Rapid Alterations of Hemispheric Dominance during Planning

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