Association of ABO Blood Group and Risk of Breast Cancer

Aly, Rabab; Yousef, Ansaf

doi:10.4172/2155-9864.1000241

Cited by 14 publications

(10 citation statements)

References 38 publications

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“…However, it has yet to be fully established the validity or otherwise of how the statistical associations between blood group and some disease risks actually translate in vivo; evidence suggests that blood group antigens may play a biological role in some disease pathogenesis [ 7 ]. ABO antigen type has been postulated from many reports as a risk factor for some cardiovascular diseases [ 8 – 10 ], cancers [ 11 – 14 ], and infectious diseases [ 15 – 17 ]. The proposed mechanism believed to underlie how ABO blood group may influence cardiovascular disease risk involves the possible regulatory effect of ABO antigens on plasma levels of von Willebrand factor (VWF) and coagulation factor VIII (FVIII) [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

Smith

Okai

Abaidoo

et al. 2018

Journal of Nutrition and Metabolism

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ABO blood group and body mass index (BMI) have individually been appraised as risk factors for certain diseases. From statistical perspective, it may be important to examine the relationship between the ABO blood antigen and BMI. This cross-sectional study involved 412 participants aged 18 to 46 at the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi. Weight and height of participants were measured for BMI calculation; blood group determination was done using antisera. Blood group O was the most prevalent (51.2%), while Rhesus-positive individuals constituted 90.3%. 6.3% of the participants were obese, while 18.7% were overweight. There was significant (p=0.006) higher prevalence of obesity in females (10.3%) than in males (3.4%). The study did not observe any significant difference by association of ABO blood group with gender (p=0.973), BMI (p=0.307), or Rhesus status (p=0.723). Regarding gender (p=0.400) and BMI (p=0.197), no statistically significant difference was observed between Rhesus blood groups. The prevalence of overweight, obesity, blood type O, and rhesus positive observed among students in this study is largely similar to what has been reported in published studies in Ghana and from other countries. Overweight and obesity were not associated with ABO blood groups or Rhesus in this study.

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Section: Introductionmentioning

confidence: 99%

Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

Smith

Okai

Abaidoo

et al. 2018

Journal of Nutrition and Metabolism

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“…Os achados deste estudo mostraram que a distribuição do grupo sanguíneo ABO em pacientes com câncer de mama foi semelhante à da população saudável e não houve correlação positiva entre idade, estado menopausal, histórico familiar de câncer e grupo sanguíneo ABO. Isso também foi observado por Aly et al 17 no Egito, onde avaliaram 160 pacientes com câncer de mama e por Akin e Altundag (2018) 18 , uma coorte nacional de 3.944 pacientes com câncer de mama na Turquia, ambos não encontraram correlação entre as características clínicas do paciente e o grupo sanguíneo.…”

Section: Resultsunclassified

Blood type evaluation in breast cancer patients at an oncology center in Agreste Pernambucano

Alves¹,

Filho²,

Larrazábal³

et al. 2020

Mundo Saúde

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Avaliação da tipagem sanguínea em pacientes com câncer de mama em centro de oncologia do Agreste Pernambucano Resumo Desde o primeiro relato de associação entre o antígeno A e o aumento de risco de câncer de estômago, diversos estudos têm avaliado o envolvimento do grupo sanguíneo ABO na patogênese do câncer. Baseando-se nesta hipótese, este estudo objetivou associar a tipagem sanguínea como fator de risco para desenvolvimento do câncer de mama em uma população feminina atendida no Centro de Oncologia de Caruaru (CEOC) em Pernambuco. O grupo 'casos' (n=50) foi composto de pacientes do sexo feminino diagnosticadas com câncer de mama com grupo sanguíneo ABO sorologicamente confirmado. O grupo 'controles' (n=50) foi obtido através de prontuários eletrônicos de pacientes sem o diagnóstico de câncer, com a mesma faixa etária. A frequência de distribuição dos grupos sanguíneos foi comparada entre os casos (48% O, 40% A, 12% B e 0% AB) e controles (44% O, 40% A, 14% B e 02% AB). Os achados deste estudo mostraram que não houve associação significativa entre câncer de mama e grupo sanguíneo ABO (p>0,05), além de não terem sido observadas diferenças significativas nas características clinicas entre pacientes com diferentes tipos do grupo sanguíneo ABO.

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“…Встановлено підвищений ризик розвитку раку молочної залози, товстої кишки, підшлунковаї залози, стравоходу, сечового міхура, яєчників, легень, шкіри, щитовидної залози, печінки з груповими еритроцитарними антигенами. Також доведено вплив антигенів груп крові АВ0, Rhesus, Kell на ступінь диференціювання злоякісних клітин, а також чутливість пухлини до терапії, загальну виживаність (Yuzhalin and Kutikhin, 2012;Pelzer et al, 2013;Urun et al, 2013;Abobaker et al, 2014;Aly et al, 2014;Cao et al, 2014;Kumar et al, 2014;Mansour et al, 2014;Nakashidze et al, 2014;Upma and Fotra, 2016). Іноді дані про розподіл антигенів еритроцитів у хворих із різною патологією неоднозначні, але наявність тих або інших еритроцитарних специфічностей у людини може бути фактором ризику виникнення певного захворювання, у тому числі й онкогематологічного (Cihan, 2014;Mansour et al, 2014;Engel et al, 2015;Flegr, 2016).…”

Section: вступunclassified

Association of group erythrocyte antigens and B-cell non-Hodgkin lymphoma

Tymoshenko

Sivkovych

Garkava

et al. 2016

VDNUBM

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We analyzed the frequency distribution of blood groups AB0, Rhesus and Kell in patients with B-cell non-Hodgkin lymphoma. An increase of D− patients (31.0%) among ill in comparison to healthy individuals (16.5%) was found. Based on published data, we exclude weakening or alteration of the D antigen for this pathology. We found an association of B-cell non-Hodgkin lymphoma and D− phenotype. It is established that the chances of developing the disease in D− individuals is 2 times higher than for D+ individuals. However, we did not find a significant association of frequency of minor antigens Rhesus (C, c, E, e, CW), K antigen Kell system, A and B antigens AB0 system and the development of B-cell non-Hodgkin lymphoma. We have analyzed the statistics of incidence of non-Hodgkin lymphoma inWestern Europeand Asian countries. We noticed a roughly twofold increase in the incidence of non-Hodgkin lymphoma inWestern Europecompared to Asian countries, where the proportion of D− individuals is almost zero. Parallel with the results of our study, it has been found that the chances of D– persons developing B-cell non-Hodgkin lymphoma are twice as high as for D+ individuals. InUkraine,BelarusandRussiathe incidence of non-Hodgkin lymphoma is almost at the level of Asian countries even though the percentage of D– individuals corresponds to Western European countries (15–16%). This can be explained by other genetic factors, or reduction in quality of care and diagnostics in post-Soviet countries compared toWestern Europe. Thus, D antigen may have a protective role in the morbidity of non-Hodgkin lymphoma.

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Association of ABO Blood Group and Risk of Breast Cancer

Cited by 14 publications

References 38 publications

Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

Blood type evaluation in breast cancer patients at an oncology center in Agreste Pernambucano

Association of group erythrocyte antigens and B-cell non-Hodgkin lymphoma

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