2013
DOI: 10.7314/apjcp.2013.14.9.5145
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Association of DNA Base-excision Repair XRCC1, OGG1 and APE1 Gene Polymorphisms with Nasopharyngeal Carcinoma Susceptibility in a Chinese Population

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Cited by 34 publications
(33 citation statements)
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“…Nowadays, A large of studies about Genetic polymorphisms (Fayaz;Gao et al, 2013;Li et al, 2013) has been reported, but in these studies, the relationship between the combined effect of different Gene loci has not been researched.To our knowledge, we have demonstrated that the relationship between combined effect of IL17A, IL17F genotypes and silicosis. And this is the first study shows that IL-17F 7488A/G polymorphism may contribute to the risk of silicosis.…”
Section: Discussionmentioning
confidence: 99%
“…Nowadays, A large of studies about Genetic polymorphisms (Fayaz;Gao et al, 2013;Li et al, 2013) has been reported, but in these studies, the relationship between the combined effect of different Gene loci has not been researched.To our knowledge, we have demonstrated that the relationship between combined effect of IL17A, IL17F genotypes and silicosis. And this is the first study shows that IL-17F 7488A/G polymorphism may contribute to the risk of silicosis.…”
Section: Discussionmentioning
confidence: 99%
“…The relation of DNA repair gene polymorphism and cancer risk has been widely studies (Li et al, 2013;Yang et al, 2013). Previous studies concerning the association between ERCC4 rs1800067 A/G polymorphism and risk of cancer were controversial.…”
Section: Discussionmentioning
confidence: 99%
“…Genetic variations in BER may result in reduced or defected repair 1 capability and accumulated DNA damage consequently leading to permanent mutations in the genome, which may ultimately contribute to carcinogenesis. Therefore, base excision repair is a universal event in cells for preventing mutagenesis Alanazi et al, 2013;Li et al, 2013;Luo et al, 2014).…”
Section: Introductionmentioning
confidence: 99%
“…Variants in different regions of APEX1 gene have been identified and found to influence the susceptibility and progression of different cancers including lung cancer (Lo et al, 2009;Lu et al, 2009), bladder cancer , glioblastoma , cervical cancer , nasopharyngeal carcinoma (Li et al, 2013) and breast cancer (Zang et al, 2006;Kang et al, 2013). Previously 18 single nucleotide polymorphisms (SNPs) in APEX1 have been identified of which, one functional SNPs in promoter region (−656 T>G, rs1760944) and one in the fifth exon (1349 T>G, Glu148Asp, rs1130409) have been widely investigated : Li et al, 2013.…”
Section: Introductionmentioning
confidence: 99%
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