Association of gout and depression: A systematic review and meta‐analysis

Lin, Song Chang; Zhang, Huaqi; Ma, Aiguo

doi:10.1002/gps.4789

Cited by 22 publications

(17 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During gout flares, emotional impacts were even more severe, with patients reporting despondency and frustration from their pain and immobility, compounded by the need to explain themselves to others and how others perceived their illness. These results coincide with recent research demonstrating a significant association between depressive symptoms and frequency of gout flares 22,23 . This raises questions as to how emotional wellbeing can be improved among patients with gout, potentially through mental health services, or by improving outcomes through better treatment.…”

Section: Discussionsupporting

confidence: 87%

“…These results coincide with recent research demonstrating a significant association between depressive symptoms and frequency of gout flares. 22,23 This raises questions as to how emotional wellbeing can be improved among patients with gout, potentially through mental health services, or by improving outcomes through better treatment. Demonstrating how ULTs can reduce the emotional impacts of gout may also be an avenue for improving adherence.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Australian patient perspectives on the impact of gout

et al. 2020

View full text Add to dashboard Cite

Gout and its management are of notable significance in Australia. The prevalence of gout in Australia has steadily increased since 1968, 1 and is now reported to be somewhere between 1.6% 1 to 6.8%. 2 Furthermore, at least one in every 100 general practice consults involve patients with gout. 3 The prevalence is even higher in at risk populations, with 16.5% of Australian men over 65 years reported as having gout, 1 and 9.7% of Aboriginal males in certain communities. 4 However, despite its prevalence, in the Australian clinical setting gout is sub-optimally managed. Rates of urate-lowering therapy (ULT) prescription and serum urate monitoring are low, 1,2 and patients report inadequate education regarding gout management from their doctors. 5 Patients also have limited understanding of how to recognize gout flares, and how to manage their medications. 6 Poor patient knowledge hinders effective management, through consequent failure of adherence to lifestyle changes and medications. 7 Australian studies have demonstrated adherence to ULT at 55%, 2 significantly lower than other medications for comparable chronic diseases. 8 Furthermore, clinicians' perceptions that gout is self-inflicted can limit patient care. 9 This highlights the need to study the experiences of patients with gout, to better

show abstract

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Australian patient perspectives on the impact of gout

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Our linguistic analyses reflect greater disability in social and leisure activities and lower positive emotion for those searching for medical conditions such as gout or arthritis, compared to people who do not search for these conditions. Although it cannot be assumed that all participants searching for gout had the condition, these findings align with prior studies which have shown higher rates of depression (26), and reduced social participation in people with gout (27).…”

Section: Discussionsupporting

confidence: 89%

Googling Gout: Exploring Perceptions About Gout Through a Linguistic Analysis of Online Search Activities

Jordan

Pennebaker

Petrie

et al. 2019

Arthritis Care & Research

View full text Add to dashboard Cite

The perception of gout as a condition managed by dietary strategies aligns with online information-seeking about the disease and its management. In contrast, people searching about arthritis focus more on medical strategies. Linguistic analyses reflect greater disability in social and leisure activities and lower positive emotion for those searching for gout or arthritis. This article is protected by copyright. All rights reserved.

show abstract

“…In addition, steroid treatment for gout may induce muscle weakness and osteoporosis and increase the incidence of injury. A recent meta-analysis demonstrated a strong positive relationship between gout and depression [22]. We can reasonably speculate that the greater incidence of suicide and poisoning in gout patients is related to depressive disorders.…”

Section: Discussionmentioning

confidence: 61%

Association Between Gout and Injury Risk: A National Retrospective Cohort Study

Chou

Lin

et al. 2020

IJERPH

View full text Add to dashboard Cite

The association between gout and injury remains unclear. This study aimed to investigate the injury risk in patients with gout. Using the Longitudinal Health Insurance Database (LHID) from 2000 to 2010 in Taiwan, patients with gout (group CFG) and those without gout (group C) were enrolled for further analysis. The CFG group was separated into two subgroups (with and without medication) to determine whether the risk of injury was reduced with drug intervention. The follow-up period was defined as the time from the initial diagnosis of gout to the date of injury. A total of 257,442 individuals were enrolled in this study, with 85,814 people in group CFG and 171,628 people in group C. Using Cox regression analysis, group CFG showed a significant increase in the risk of injury. Traffic injuries, poisoning, falls, crushing/cutting/piercing injury, and suicides were prominent among these injuries. Furthermore, when urate-lowing drugs were used to treat the CFG group, there were no significant differences in the occurrence of injury. Patients with gout had an increased risk of injury overall, and drug intervention did not lower the risk of injury in these patients.

show abstract

Association of gout and depression: A systematic review and meta‐analysis

Abstract: Our meta-analysis demonstrates a positive association between gout and depression. Further large-scale prospective cohort studies are needed to investigate the causality between gout and depression.

Cited by 22 publications

References 38 publications

Australian patient perspectives on the impact of gout

Australian patient perspectives on the impact of gout

Googling Gout: Exploring Perceptions About Gout Through a Linguistic Analysis of Online Search Activities

Association Between Gout and Injury Risk: A National Retrospective Cohort Study

Contact Info

Product

Resources

About