Association of Ramadan daytime fasting with ocular surface inflammation and dry eye

Armstrong, Brian K.; Coc, Ivana Romac; Agarwal, Prateek; Smith, Scott D.; Navon, Samuel E.

doi:10.1007/s10792-019-01133-5

Cited by 8 publications

(3 citation statements)

References 43 publications

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“…In this study, the decrease of MMP-9 was observed until T5. Unfortunately, there was no comparison study available in regard to MMP-9, except one that measured MMP-9 from the ocular surface ( 52 ). Furthermore, it seems the benefit of fasting in different diseases could be mediated by the decrease of MMP-9.…”

Section: Discussionmentioning

confidence: 99%

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

et al. 2021

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Ramadan fasting (RF) is a type of diurnal intermittent fasting. Previous studies reported the benefits of RF in healthy subjects on mood and health related to quality of life (QoL). Cortisol and brain-derived neurotrophic factor (BDNF) have been shown to play a role in mood, body composition parameters, and health-related QoL. This study aimed at elucidating the mechanism of the benefit of RF, particularly cortisol and BNDF and their association with mood and QoL. Insulin growth factor-1 (IGF-1), interleukin (IL)-8, matrix metalloproteinase (MMP)-9, and myoglobin were determined. Thirty-four healthy men and women were recruited. Serum from peripheral venous blood samples was collected at five time points: 1 week before RF (T1); mid of RF (T2), last days of RF (T3), 1 week after RF (T4), and 1 month after RF (T5). The amounts of biological mediators in the serum samples were determined by enzyme-linked immunosorbent assay (ELISA) and Luminex assays. BDNF and cortisol significantly decreased at T3 (p < 0.05) and T4 (p < 0.001) compared to T1, respectively. It seems the benefits of RF for mood-related symptoms are mediated by different biological mediators, particularly cortisol and BDNF.

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Section: Discussionmentioning

confidence: 99%

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

et al. 2021

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“…In agreement with our findings, a previous study reported no significant association between OSDI score and Ramadan fasting although they did not quantify the participants’ beverage intake. 23 …”

Section: Discussionmentioning

confidence: 99%

Dry Eye Disease Symptoms and Its Association with Daily Beverage Intake Among Adults in Saudi Arabia

Alsahly¹,

Aldawsari²,

Alzaidy³

et al. 2022

OPTH

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Purpose To evaluate the association between dry eye disease (DED) symptoms and daily beverage intake among adults in Saudi Arabia. Patients and Methods In this cross-sectional, questionnaire-based study, we distributed an online questionnaire to men and women older than 18 years living in Saudi Arabia. The questionnaire consisted of items related to the sociodemographic characteristics of the participants and two validated indices: the Ocular Surface Disease Index (OSDI) and the brief 15-item Beverage Intake Questionnaire (BEVQ-15). Participants were excluded if they were aged less than 18 years; wore contact lenses; had existing eye disease (excluding refractive errors), history of eye surgery (including corrective eye surgeries), or autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, Sjogren’s syndrome); or were currently taking specific medications including antidepressants, antihistamines, and diuretics. Results After applying the study exclusion criteria, a total of 615 participants were included in the statistical analysis. The majority of participants were 18–34 years old (450, 73.2%), and men (381, 62%) exceeded women (234, 38%) by approximately 1.5-fold. OSDI scores showed that 344 participants (55.9%) had DED symptoms, 145 (23.6%) had mild dry eyes; and 106 (17.2%) and 93 (15.1%) had moderate and severe dry eyes, respectively. There was a significant association between sex and DED symptoms (p = 0.012); the frequency of DED symptoms in women exceeded that in men. However, no significant differences were observed with other demographic data such as age and location of residence. Although beverage intake was moderately correlated to OSDI score (R = 0.27), we found no significant association between beverage intake and DED symptoms. Conclusion This is the first study to highlight the association between DED symptoms and daily beverage intake. We found a significant association between DED symptoms and female sex. However, no significant association was found between DED symptoms and other demographic characteristics or beverage intake.

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“…Armstrong et al [56] evaluated Ramadan's fasting on the level of tear film matrix metalloproteinase-9 (MMP-9) and other standard indicators of dry eye disease in forty healthy patients without a history of ocular disease before and during Ramadan. Ocular Surface Disease Index scores, tear breakup time (TBUT), Schirmer I test, and corneal fluorescein staining were evaluated at each time point.…”

Section: Changes In the Structure And Function Of The Eye During Fastingmentioning

confidence: 99%

Ramadan fasting in health and disease (2019): A narrative review

Ali

Abdulla

Badi³

et al. 2020

Ibnosina Journal of Medicine and Biomedical Sciences

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Introduction: Literature on the health aspects of Ramadan fasting (RF) is widespread in many journals, making it less readily available to those interested in the subject. Materials and Methods: This is a narrative, nonsystematic review of international literature from two major online databases (viz., Scopus and PubMed) in 1 year (2019). The search term “RF” was used, and relevant literature was narrated in a concise thematic account excluding diabetes. Results: The publications spanned the fundamental, clinical, ethical, professional, cultural, and advocacy facets of the subject. The publications crossed the conventional disciplinary lines and geographical locations and appeared in journals with different access systems. The content is presented under relevant themes depending on the available literature. Basic coverage included changes in physiology, nutrition, and metabolism during Ramadan. Clinical aspects such as the impact of RF on kidney function, pregnancy outcome, fetal life, structure and function of eyes, and athletes' well-being received comparatively prominent coverage by researchers in 2019. Gut, liver, skin, skeleton, and blood were also covered. Other workers focused on documenting the perception, attitudes, and practices of both patients and health-care professionals during Ramadan. Conclusions: The health aspects of RF received sustained academic interest with a wide spectrum in 2019. We provided a scoping overview to help researchers and clinicians catch up quickly with the state-of-the-art today.

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Association of Ramadan daytime fasting with ocular surface inflammation and dry eye

Cited by 8 publications

References 43 publications

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

Dry Eye Disease Symptoms and Its Association with Daily Beverage Intake Among Adults in Saudi Arabia

Ramadan fasting in health and disease (2019): A narrative review

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