Associations between pyogenic liver abscess and colorectal and biliary cancers

Chong, Vui Heng; Kosasih, Sumitro; Lin, Chun‐Pin

doi:10.1093/qjmed/hcy237

Cited by 3 publications

(1 citation statement)

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“…[ 17 ] Although there are no guidelines to determine whether PLA patients should be routinely screened for colon cancer, many scholars believe that PLA is closely associated with colon cancer, especially in patients with Klebsiella pneumoniae infection and diabetes. [ 18 , 19 ] Mohan et al conducted a meta-analysis, which showed that patients with PLA had a much higher incidence of colon cancer than the general population, and over 90% of the pathogenic bacteria were Klebsiella pneumoniae. Therefore, early colon cancer screening for patients with cryptogenic KP-PLA was recommended.…”

Section: Discussionmentioning

confidence: 99%

Occult colon cancer with liver abscess and pancreatitis as the first manifestations: A case report

2023

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Introduction: Klebsiella pneumoniae-induced liver abscess (KP-PLA) is a common type of pyogenic liver abscess, severe acute pancreatitis (SAP) has high mortality, and poor prognosis in advanced colon cancer. There have been no report of SAP complicated with colon cancer after KP-PLA as so far. In this study, we reported a case of SAP secondary to KP-PLA with colon cancer for the first time, so as to provide reference for clinical diagnosis and treatment of these diseases.Patient concerns and diagnosis: A 64-year-old woman with a history of diabetes visited our hospital with abdominal pain for 5 + days. He was diagnosed with KP-PLA a month ago, which had not healed when he was admitted. He was diagnosed with SAP, and histological examination of colonic biopsy confirmed the diagnosis of moderately differentiated adenocarcinoma.Interventions and outcomes: He was treated with intravenous antibiotics and underwent modified endoscopic mucosal resection under colonoscopy. We conducted a 2-month follow-up, and there was no recurrence of liver abscess and pancreatitis. Conclusion:Screening for intestinal tumors is necessary in patients with cryptogenic liver abscess, especially KP-PLA with diabetes.

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Section: Discussionmentioning

confidence: 99%