Associations between serum vitamins and serum lipids in healthy Northeast China adults

Abstract

Objective In previous studies, serum vitamins were shown associated with lipid levels. However, evidence regarding the associations between various serum vitamins and serum lipids is limited. Therefore, the associations between serum vitamins and serum lipids were investigated in this cross-sectional study.Methods The study population included 131 adults (42 males and 89 females) ≥ 18 years of age who lived more than three years in Shenyang, Liaoning province, China. Serum lipids included total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Analysis of covariance was used to explore the associations between serum vitamins and serum lipids.Results After multiple adjustments, vitamin A and vitamin C concentrations were positively associated with LDL-C level ( P for trend < 0.05). Vitamin A, vitamin B5, and vitamin C concentrations were positively associated with TG level ( P for trend < 0.05). However, vitamin B1 concentration was negatively associated with TG level ( P for trend = 0.04). Vitamin E concentration was positively associated with HDL-C level ( P for trend = 0.02). No association was observed between vitamin concentrations and TC level.Conclusion The results in the present study indicate that serum vitamin concentrations are associated with serum lipid levels. Vitamin B1 and vitamin E concentrations were associated with a better status of lipid profiles. However, vitamin A, vitamin C, and vitamin B5 concentrations were associated with a worse status of lipid profiles.