2014
DOI: 10.1016/j.reval.2014.02.138
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Asthme et syndrome d’apnée obstructive du sommeil (SAOS) : y’a-t-il un rapport ?

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“…Asthmatics have an increased risk of sleep apnoea and apnoea can worsen asthma by increasing inflammation. [23] Recent data suggested that OSAS is an independent risk factor for asthma exacerbations. [23] Neuromechanical reflex bronchoconstriction, gastroesophageal reflux, inflammation (local and systemic), and the indirect effect on dyspnoea of OSAS-induced cardiac dysfunction have been suggested as mechanisms that lead to worsening asthma in patients with concomitant OSAS.…”
Section: Discussionmentioning
confidence: 99%
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“…Asthmatics have an increased risk of sleep apnoea and apnoea can worsen asthma by increasing inflammation. [23] Recent data suggested that OSAS is an independent risk factor for asthma exacerbations. [23] Neuromechanical reflex bronchoconstriction, gastroesophageal reflux, inflammation (local and systemic), and the indirect effect on dyspnoea of OSAS-induced cardiac dysfunction have been suggested as mechanisms that lead to worsening asthma in patients with concomitant OSAS.…”
Section: Discussionmentioning
confidence: 99%
“… [23] Recent data suggested that OSAS is an independent risk factor for asthma exacerbations. [23] Neuromechanical reflex bronchoconstriction, gastroesophageal reflux, inflammation (local and systemic), and the indirect effect on dyspnoea of OSAS-induced cardiac dysfunction have been suggested as mechanisms that lead to worsening asthma in patients with concomitant OSAS. In patients whose asthma is not controlled by drug therapy, the presence of OSAS should be investigated and properly managed.…”
Section: Discussionmentioning
confidence: 99%
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