Asymptomatic superior vena cava thrombosis as a manifestation of secondary antiphospholipid syndrome in a female presenting with anemia and bad obstetric history

A Case of Systemic Lupus Erythematosus without Antiphospholipid Syndrome Causing Superior Vena Cava Syndrome

“…Similarly, another case of asymptomatic SVC thrombosis as a manifestation of SLE with APS (also known as secondary APS) in a 34-year-old woman with recurrent spontaneous abortions and hemolytic anemia has been reported. 14 This patient had no overt signs of SVC obstruction due to the development of collateral vessels. Moreover, SVC thrombosis has also been reported in association with drug-induced lupus with circulating anticoagulants.…”

“…11 A similar case was also reported by Kingetsu et al, 12 SVC syndrome (caused by thrombosis) as a presenting feature of SLE is comparatively rare and whatever few cases are reported to date are all cases of lupus associated with APS. 13 , 14 A case of SLE associated with anticardiolipin antibodies presenting as SVC syndrome has been reported previously. 13 The 19-year-old woman described in this report had thrombotic occlusion of SVC, which successfully responded to immunosuppressives and intravenous thrombolytics.…”