Atopik dermatit tanı yaşının ek alerjik hastalık gelişimi üzerine etkisi

Abstract

Aim:The aim of this study is to determine the effect of age at the time of diagnosis on development of additional allergic diseases and aeroallergen sensitivity in pediatric patients with a diagnosis of AD. Material and Method: The study includes 114 pediatric patients who were diagnosed as atopic dermatitis according to Hanifin and Rajka criteria. After all patients were divided into two groups according to age at the time of diagnosis as less than 24 months and more than 24 months, total serum IgE, inhalant spesific IgE, ECP levels were measrued and skin prick tests were performed. The additional allergic diseases developed during the followup were recorded. Results: 90 patients (%78.9) were under 24 months of age, 24 (%21.1) patients were over 24 months of age, when the patients were gouped according to age at the time of diagnosis. In our study group, mean age at the time of diagnosis was 14.0±21.4 months, the duration for development of an additional allergic disease was 23.8±22.3 months and mean follow-up period was 58.7±41.2 months (min.8 monthsmax.180 months ; median 50.5 months). In the group who were under 24 months of age at the time of diagnosis, a significant difference was determined for development of asthma in the future (p=0.042). Conclusions:To prevent the allergic process in cases in whom atopic dermatitis findings start at an early age, the families should be warned about the allergic diseases associated with the repiratory system and should protect their children from inhalant allergens. (Turk Arch Ped 2011; 46: 299-303)