2021
DOI: 10.3389/fneur.2021.661391
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Atrioventricular Conduction in Mesial Temporal Lobe Seizures

Abstract: Purpose: Asymmetric cerebral representation of autonomic function could help to stratify cardiac complications in people with epilepsy, as some seizures are associated with potentially deleterious arrhythmias including bradycardia and atrioventricular (AV) conduction block. We investigated seizure-related changes in AV conduction and ascertained whether these alterations depend on the hemisphere in mesial temporal lobe epilepsy (mTLE).Methods: EEG and ECG data of people with pharmacoresistant mTLE undergoing p… Show more

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“…However, the essential triggering factor for advanced AV block in our patient was unclear. We thought that epileptic seizure itself might modulate autonomic nerve activity [14,15] and AV conduction might be inhibited by epileptic origin in the brain like temporal lobe seizures [16]. Furthermore, using lacosamide and tizanidine medications probably facilitated the impact of epileptic seizure via autonomic modulation on AV conduction.…”
Section: Discussionmentioning
confidence: 99%
“…However, the essential triggering factor for advanced AV block in our patient was unclear. We thought that epileptic seizure itself might modulate autonomic nerve activity [14,15] and AV conduction might be inhibited by epileptic origin in the brain like temporal lobe seizures [16]. Furthermore, using lacosamide and tizanidine medications probably facilitated the impact of epileptic seizure via autonomic modulation on AV conduction.…”
Section: Discussionmentioning
confidence: 99%