2007
DOI: 10.1590/s0004-282x2007000600024
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Atypical subacute sclerosing panencephalitis: case report

Abstract: -Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory disorder of the central nervous system with both poor prognosis and high mortality. The disease has been related to a persistent and aberrant measles virus infection and no effective treatment has been available. We report a case of SSPE with atypical features including seizures at onset and a fulminant course in a 8 years-old boy who had been previously immunized against measles.KEY WORDS: subacute sclerosing panencephalitis, measles, i… Show more

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Cited by 9 publications
(5 citation statements)
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“…Early-onset SSPE with short onset latency is generally associated with congenital and neonatal measles infection. Zwiauer et al diagnosed a case of SSPE as early as 4 months of age after perinatally acquired measles infection [8]. It is seen that children with early age of onset of measles infection have a shorter latency period as seen with our case.…”
Section: Discussionsupporting
confidence: 69%
“…Early-onset SSPE with short onset latency is generally associated with congenital and neonatal measles infection. Zwiauer et al diagnosed a case of SSPE as early as 4 months of age after perinatally acquired measles infection [8]. It is seen that children with early age of onset of measles infection have a shorter latency period as seen with our case.…”
Section: Discussionsupporting
confidence: 69%
“…(6)In this child, a latent period of 7-8 years was noted after which symptoms started in form of seizures initially generalised tonic-clonic followed by jerky movements associated with behavioural abnormalities.. There was difficulty in vision (8) . There was no associated fever , any other systemic complaints .There is a positive history of measles infection with unvaccinated patient.…”
Section: Case Reportmentioning
confidence: 85%
“…Atypical features include unusual age of onset, visual loss, seizures and other focal symptoms as initial presentations, a lack of SSPE-specific EEG pattern, and atypical fast progression of disease [6]. While ophthalmological symptoms such as optic atrophy, chorioretinitis, and papilledema are commonly associated with SSPE [4][5][6][7].…”
Section: Discussionmentioning
confidence: 99%