Audit of Partial and Complete Hydatidiform Moles in Tertiary Care Hospital JPMC, Karachi

Abstract

Objective: This study aims to investigate the clinical presentation, frequency and histopathology of hydatidiform mole, as well as to determine the clinical significance of such histopathological examination. Material and method: This was a retrospective study undertaken at the Department of Pathology Bmsi Jpmc Karachi from January 1st, 2016 to November 31st, 2021.All molar pregnancy cases were thoroughly examined, taking into account their age, gestational age, signs and symptoms, clinical diagnosis where available and histopathology. Results: Total 73 cases of hydatidiform moles were obtained during study period. There were 64.3% partial hydatidiform moles and 35.6 % complete moles. The majority of the patients were between the ages of 21 and 35 years. Bleeding per vaginum was the most prevalent presenting symptom. The period of gestation in majority of patients (54.7%) was 2–5 months. Conclusion: We came to the conclusion that partial mole was more common than complete mole .Histopathlogical findings of PHM differ from CHM.The diagnosis of molar pregnancy is helped by histopathological study of products of conception (POC), that can be missed on clinical and ultrasound assessment. As a result, products of conception should be subjected to histological investigation on a regular basis to avoid missing the diagnosis of molar pregnancy. Keywords: Molar pregnancy,Trophoblastic hyperplasia, Hydatidiform mole,

A Research Study on Molar Pragnencies, Treatment, Causes and its Effect on Human Body

“…About 71% patients were facing higher issues [15]. Different therapies were performed on these patients to give them self-awareness and also give them self-knowledge about their issues [16]. Higher risk patients give some more time to get resigned from hospital and move to their homes after treatment.…”

“…As discussed earlier, molar pregnancy was considered as not proper development of embryo occur and pregnancy does not exist for so long and it goes to end [1]. Now thing to determine is that why this type of issues develop which leave serious outcomes [2].…”

“…They make this study to note down the reason of miscarriage and under development of fetus [5]. Risks they are facing have hazardous effects or not [6].…”