Auditory Event-Related P300 Potentials in Rheumatoid Arthritis Patients

Neuronal Correlates of Cognitive Control Are Altered in Women With Endometriosis and Chronic Pelvic Pain

“…Non-target P3a amplitudes (eP3a and lP3a) in the endometriosis group were attenuated compared to HCs, a finding in line with previous studies (Ozgocmen et al, 2003;Yoldas et al, 2003;Alanoglu et al, 2005;Hamed et al, 2012;Tomasevic-Todorovic et al, 2015;Samartin-Veiga et al, 2019). Non-target/NoGo P3a typically peaks 250-400 ms in oddball and Go/NoGo tasks and is topographically defined by a frontocentral distribution of positive activity, as shown in the HC group, peaking at 352 ms. As with the other P3 components, P3a has not been widely explored in CPTs, however, Karamacoska et al (2015Karamacoska et al ( , 2019 showed distinct non-target fronto-central P3as peaking between 250 and 350 ms in a visual cued CPT (Gordon variant).…”

“…As hypothesized, target P3b and SW amplitudes were reduced in the endometriosis compared to the HC group (Ozgocmen et al, 2003;Yoldas et al, 2003;Alanoglu et al, 2005;Hamed et al, 2012;Tomasevic-Todorovic et al, 2015;Samartin-Veiga et al, 2019). P3b has several functional interpretations, particularly in the oddball and Go/NoGo task context [e.g., context-updating (Donchin and Coles, 1988;Brydges and Barceló, 2018), stimulusresponse pattern activation and updating (Steiner et al, 2013b;Verleger et al, 2016), response monitoring (Verleger et al, 2005;Fogarty et al, 2020)], yet is under-explored in cued CPT tasks such as the AX-CPT.…”

“…For example, reduced auditory oddball and visual multi-source interference task P3 amplitudes are observed in fibromyalgia compared to controls (Ozgocmen et al, 2003;Yoldas et al, 2003;Alanoglu et al, 2005;Samartin-Veiga et al, 2019). Similarly, auditory oddball P3 amplitudes are reduced in rheumatoid arthritis compared to controls (Hamed et al, 2012;Tomasevic-Todorovic et al, 2015), and inversely correlated with pain intensity (Tomasevic-Todorovic et al, 2015). Some studies report no difference in visual stop-signal task P3 amplitude between people with fibromyalgia and controls (González-Villar et al, 2019), or the opposite relationship (i.e., larger visual oddball P3 amplitudes and positively correlated with pain intensity) following upper limb amputation compared to controls (Karl et al, 2004).…”

“…This study was the first that aimed to elucidate the neuronal correlates of cognitive control in women who have endometriosis CPP. Compared to controls, it was hypothesized that women with endometriosis and CPP would have higher pain scores, poorer behavioral performance (Suhr, 2003;Alanoglu et al, 2005;Moriarty et al, 2011;Berryman et al, 2014;Tamburin et al, 2014) and smaller P3 amplitudes (Ozgocmen et al, 2003;Alanoglu et al, 2005;Hamed et al, 2012;Tomasevic-Todorovic et al, 2015;Whitaker et al, 2016;Samartin-Veiga et al, 2019), no difference in P3 latencies (Ozgocmen et al, 2003;Alanoglu et al, 2005), and that P3 amplitudes would inversely correlate with pain severity (Tomasevic-Todorovic et al, 2015); overlapping P3 peaks were explored for the first time with temporal principal components analysis (PCA).…”

Altered Neurocognitive Processing of Tactile Stimuli in Patients with Complex Regional Pain Syndrome

“…Lastly, it is instructive to note that digit misperceptions occur in other types of chronic pain 21 . However, P300 responses from visual or auditory oddball stimuli can be either increased or decreased depending on the population of chronic pain patients studied 18,40 . Further research is required to identify common and unique mechanisms driving these effects in patients with different diagnoses.…”