Abstract-Numerical analysis in combination with the experimental data for Cr 2+ :ZnSe as well as Ti:sapphire lasers reveal the following main mechanisms of multiple-pulse generation for the Kerr-lens mode-locked solid-state lasers: 1) continuum amplification due to a spectral loss growth for ultrashort or chirped pulses and 2) a bounded perturbation rise for high-energy pulses. The role of such laser parameters as gain saturation and relaxation, saturable and unsaturable loss, self-phase modulation, Kerr-lensing, and pump intensity is analyzed. This analysis provides basic directions for single-pulse stability enhancement and for multiple-pulse generation control.