Autopsy and pre-mortem diagnostic discrepancy review in an Irish tertiary PICU

O’Rahelly, Mark; McDermott, Michael; Healy, Martina

doi:10.1007/s00431-021-04155-3

Cited by 3 publications

(2 citation statements)

References 20 publications

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“…In their study M. O'Rahelly et al observed a 40% reduction in the autopsy rate [14] and other studies in the literature [15][16][17].…”

Section: Discussion and Literature Reviewmentioning

confidence: 63%

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Salzillo,

Basile,

Cazzato

et al. 2024

Preprint

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Introduction. Autopsy is a medical procedure that consists of the corpse’s examination to determine the cause of death and obtain information on pathological conditions or injuries present in the body. In recent years there has been a reduction in hospital autopsies and an increase in forensic autopsies. Material and methods. A retrospective observational study was conducted on the reports of all the 645 hospital autopsies performed at Polyclinic of Bari from 2006 to 2021.Results. Group A, 2006-2009, 174 cases were studied: 58% male, 58% adults, 55% neonatology, pulmonary disease was the cause of death in 23%, and 55% of discrepancy between clinical and autopsy diagnosis. Group B, 2010-2013, comprised 119 cases: 52% male, 46% infants, 48% neonatology, pulmonary disease was the cause of death in 25%, and 56% of discrepancy between clinical and autopsy diagnosis. Group C, 2014-2017, comprised 168 cases: gender equality, 37% infants, 25% gynecology, pulmonary disease was the cause of death in 24%, and 58% of discrepancy between clinical and autopsy diagnosis. Group D, 2018-2021 comprised 184 cases: 56% male, 38% adult, 32% gynecology, pulmonary disease was the cause of death in 27%, and 58% discrepancy between clinical and autopsy diagnosis.Conclusion. The study of hospital autopsies at the Polyclinic of Bari shows that the discrepancy between clinical and autopsy diagnosis is around 56.75%. Thus, the hospital autopsy is helpful in the modern age, especially for diagnosing fetal and neonatal diseases.

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“…In their study M. O'Rahelly et al observed a 40% reduction in the autopsy rate [14] and other studies in the literature [15][16][17].…”

Section: Discussion and Literature Reviewmentioning

confidence: 63%

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Salzillo,

Basile,

Cazzato

et al. 2024

Preprint

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“…Про частоту проведення автопсій у померлих новонароджених не повідомлялося. Було лише зазначено, що частота автопсій у загальній групі пацієнтів відділень інтенсивної терапії протягом періоду спостереження становила 25 %, ця частота знизилась на 40 % з 2000-2002 років частково через небажання сімей давати згоду, частково через небажання медичного персоналу обговорювати перспективу розтину з родинами [19].…”

Section: результати та обговоренняunclassified

Diagnostic errors in neonatology

Mavropulo¹,

Vlasov²,

Vereshchak³

2023

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Background. Тhe incidence of diagnostic errors in neonatology and their impact on children’s health remain relatively unknown. The limited available evidence, however, suggests that diagnostic errors in the neonatal unit result in significant and long-term consequences. The purpose of the study was to generalize the literature data on diagnostic errors in neonatal units in view of their prevalence, impact on health status, and contributing factors. Materials and methods. The search was done in the PubMed Central® database using the keywords “misdiagnosis”, “diagnostic errors”, “neonatal intensive care unit”, “neonatal unit”, “neonatology”, “newborns”. Results. Methods to identify diagnostic errors were analyzed: autopsy results, consideration of complaints and conflicts, voluntary survey of doctors and patients, symptom-disease pair (SPADE approach), trigger methodology, Safer Dx Instrument (measurement and improvement of diagnostic safety). The incidence of detecting diagnosis errors ranged from 19.2 % when analyzing pathology studies (including 3.7 % of those that harmed a patient) to 6.2 % when using Safer Dx Instrument (including 8.0 % of those that that harmed a patient). A real assessment of this situation can be provided by a combination of the above methods. Conclusions. Further research is needed to better quantify misdiagnosis in neonatal intensive care units and to identify potential strategies to reduce its incidence or mitigate the harm associated with misdiagnosis.

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Value of autopsy in the modern age: Discrepancy between clinical and autopsy diagnoses

Salzillo,

Basile,

Cazzato

et al. 2024

World J Exp Med

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BACKGROUND Autopsy is a medical procedure that consists of the examination of the corpse to determine the cause of death and obtain information on pathological conditions or injuries. In recent years, there has been a reduction in hospital autopsies and an increase in forensic autopsies. AIM To evaluate the utility of autopsy in the modern age and the discrepancy between clinical and autopsy diagnoses. METHODS A retrospective observational study was conducted on the reports of all 645 hospital autopsies performed at Polyclinic of Bari from 2006 to 2021. RESULTS Group A, 2006-2009, 174 cases were studied: 58% male, 58% adults, 55% neonatology; pulmonary disease was the cause of death in 23% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 55% of cases. Group B, 2010-2013, 119 cases: 52% male, 46% infants, 48% neonatology; pulmonary disease was the cause of death in 25% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 56% of cases. Group C, 2014-2017, 168 cases: sex equality, 37% infants, 25% gynecology; pulmonary disease was the cause of death in 24% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 58% of cases. Group D, 2018-2021, 184 cases: 56% male, 38% adult, 32% gynecology; pulmonary disease was the cause of death in 27% of cases; and there was a discrepancy between clinical and autopsy diagnosis in 58% of cases. CONCLUSION The study of hospital autopsies reveals a 56.75% discrepancy between clinical diagnosis and autopsy, highlighting the importance of autopsies, especially for fetal and neonatal diseases, which represent 59% of cases.

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Autopsy and pre-mortem diagnostic discrepancy review in an Irish tertiary PICU

Cited by 3 publications

References 20 publications

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Diagnostic errors in neonatology

Value of autopsy in the modern age: Discrepancy between clinical and autopsy diagnoses

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