Avaliação in Vitro Do Processo De Adesão De Macrófagos J774 Com Arcabouços 3d De Biopolímero De Cana-De-Açúcar

Ferreira, Laryssa Kathleen Mendonça; Muniz-Filho, Eduardo; Oliveira, Erwelly Barros de; Paz, Silvânia Tavares; Santos, Fábio André Brayner dos; Alves, Luíz Carlos; Aguiar, José Lamartine de Andrade; Silva, Eliete Cavalcanti da; Medeiros, Paloma Lys de

doi:10.5151/biofisica2017-011

Cited by 1 publication

(2 citation statements)

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“…The association between the multi-perforated film and the BC gel, stimulates and leads to cell growth in the wound bed, because by acting as a framework [25] it favors the proliferation of granulation tissue and superficialization of the lesion [10,14]. Important property for healing, since it is depends not only on the epithelialization of the edges, but also on the granulation and superficialization of the bed [26].…”

Section: Discussionmentioning

confidence: 99%

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Bacterial cellulose an effective material in the treatment of chronic venous ulcers of the lower limbs

Silva

Albuquerque

Pinto

et al. 2021

J Mater Sci: Mater Med

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Chronic venous ulcers (CVU) of the lower limbs (LL) are common and cause psychological changes and significant social impact, as they make the patient susceptible to pain, absence from work and social bonds. Some materials are suggested as dressings for the treatment of CVU, but they are expensive and are generally not available for use in public health services. To evaluate the efficacy of the treatment for lower limbs (LL) chronic venous ulcer (CVU) using bacterial cellulose (BC), gel and multi-perforated film associated. A randomized controlled clinical-intervention study was performed among participants with LL CVU, divided into two groups: experimental (EG), treated with BC wound dressing and control (CG), treated with a cellulose acetate mesh impregnated with essential fatty acids (Rayon®). The participants were followed for 180 days, evaluated according to the MEASURE methodology. Thirty-nine patients were treated, 20 from the EG and 19 from the CG. In both groups, the wound area decreased significantly (p < 0.001), the healing rate was similar to the CG. The mean number of dressing changes in the SG was 18.33 ± 11.78, while in the CG it was 55.24 ± 25.81, p < 0.001. The healing dressing of bacterial cellulose, gel and associated film, when stimulating the epithelization of the lesions, showed a significant reduction in the initial area, with a percentage of cure similar to the Rayon® coverage. In addition to requiring less direct manipulation of ulcers.

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Section: Discussionmentioning

confidence: 99%

“…BC is a flexible material, molds to the area that is applied, acts as a protective mechanical barrier, framework for cell migration and interaction, promotes neovascularization and, by facilitating cell colonization, creates an environment conducive to the healing process [20,[25][26][27][28][29][30].…”

Section: Introductionmentioning

confidence: 99%