Avian influenza: recent developments

Capua, Ilaria; Alexander, D. J.

doi:10.1080/03079450410001724085

Cited by 292 publications

(207 citation statements)

References 55 publications

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“…The outbreaks of highly pathogenic avian influenza viruses around the globe in the past few years have been devastating for the countries concerned (Capua & Marangon, 2003;Capua & Alexander, 2004), and have created fears with the public (Swayne & Beck, 2004). Attention has not only been on the epidemics in the major poultry species, the domestic fowl (Liu et al ., 2003;de Wit et al ., 2004;Ellis et al ., 2004a, b;Lee et al ., 2004a;Armin et al ., 2004), but also in minor species, including turkeys , commercial ducks (Kwon et al ., 2005), and waterfowl and other wild birds (Ellis et al ., 2004a).…”

Section: Viruses Of Wild Birds and Minor Domestic Speciesmentioning

confidence: 99%

Coronaviruses in poultry and other birds

2005

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Section: Viruses Of Wild Birds and Minor Domestic Speciesmentioning

confidence: 99%

Coronaviruses in poultry and other birds

2005

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“…Over the past decade, highly pathogenic avian influenza virus (HPAIV) has raised alarming concerns and has remained an unsolved problem not only for public health but also as a disease of economic importance, and it poses a continuous threat connected mainly with animal reservoirs (Capua & Alexander, 2004, 2006. Early detection is crucial in prevention and control of avian influenza virus (AIV) outbreaks, particularly when H5 and H7 subtypes are involved.…”

Section: Introductionmentioning

confidence: 99%

Persistence of highly pathogenic avian influenza virus (H7N1) in infected chickens: feather as a suitable sample for diagnosis

Busquets

Abad

Alba

et al. 2010

Journal of General Virology

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“…These types of vaccines have several advantages, including their use in differentiating infected from vaccinated animals (DIVA) strategies. This system was developed to support the eradication programmes in the presence of several introductions of AI viruses (Capua & Alexander, 2004;. Previous studies have shown that vaccine containing the H5N2 A/chicken/Mexico/232/94/CPA strain is protective in chickens and ducks against H5N1 HPAI viruses of the Eurasian lineage despite the low haemagglutination (HA) homology between the vaccine strain and the field virus (Swayne et al, 2006;Van der Goot et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the protection induced by avian influenza vaccines containing a 1994 Mexican H5N2 LPAI seed strain against a 2008 Egyptian H5N1 HPAI virus belonging to clade 2.2.1 by means of serological andin vivotests

et al. 2010

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Since 2006 Egypt has been facing an extensive epidemic of H5N1 highly pathogenic avian influenza (HPAI) with a huge number of outbreaks both in rural and intensively reared poultry areas. The use of efficacious vaccines in this country has been, and still remains, essential for the control and possible eradication of HPAI. The present study was performed to establish whether the administration of inactivated vaccines containing an H5 virus belonging to a different lineage to the Eurasian H5N1 HPAI viruses guarantees protection from clinical signs, provides significant immune response and is able to achieve a reduction of viral shedding in the face of a challenge with a contemporary H5N1 virus isolated in Egypt. Despite the genetic and antigenic differences between the vaccine strain (H5N2/Mexico) and the challenge strain (H5N1/ Egypt), confirmed by molecular and serological (haemagglutination inhibition) tests, it was established that the immune response induced by these conventional vaccines is sufficient to prevent infection in the majority of birds challenged with a contemporary H5N1 Egyptian strain. The data reported in this study also indicate that there may be a low degree of correlation between haemagglutination inhibition titres, clinical protection and reduction of shedding.

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Avian influenza: recent developments

Cited by 292 publications

References 55 publications

Coronaviruses in poultry and other birds

Coronaviruses in poultry and other birds

Persistence of highly pathogenic avian influenza virus (H7N1) in infected chickens: feather as a suitable sample for diagnosis

Evaluation of the protection induced by avian influenza vaccines containing a 1994 Mexican H5N2 LPAI seed strain against a 2008 Egyptian H5N1 HPAI virus belonging to clade 2.2.1 by means of serological andin vivotests

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