Axillary Basal Cell Carcinoma

LeSueur, Benjamin W.; DiCaudo, David J.; Connolly, Suzanne M.

doi:10.1046/j.1524-4725.2003.29346.x

Cited by 22 publications

(27 citation statements)

References 13 publications

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“…Many treatment methods, including surgery, laser, cryotherapy, electrocautery and radiotherapy, can be used in the treatment of skin cancer, and surgical treatment is the gold standard (1,4). The 5-year cure rate of surgical treatment can reach 90% or even higher, but these treatment methods are usually followed by a persistent recurrence rate, that even if treated successfully, are likely to affect the patient's appearance (12,13).…”

Section: Discussionmentioning

confidence: 99%

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Surgery combined with local 5-aminolevulinic acid-photodynamic therapy on skin cancer and its effect on the expression of cyclophilin A, cyclophilin B and CD147

Guo¹,

Han²

2017

Oncology Letters

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The study evaluated an approach to treat skin cancer using surgery combined with local 5-aminolevulinic acid-photodynamic therapy (ALA-PDT). Seventy-six patients with skin cancer who were admitted to the Liaocheng People's Hospital from May 2014 to April 2015 were randomly divided into a control and an observation group (38 cases in each). The patients in the control group were treated with ALA-PDT alone. Those in the observation group were first subjected to surgical treatment, and then treated with ALA-PDT. The treatment efficacies of the two groups were compared. The expression of cancer markers CyPA, CyPB and CD147 were detected by immunohistochemical methods before and after the treatment. Our results showed the average healing time of the wounds of patients in the observation group was shorter, the number of treatments needed was less, the efficacy rate and the lesion appearance satisfaction were significantly higher, and the recurrence rate at 12 months after treatment and the incidence of adverse reactions were both significantly lower. Additionally, the levels of CyPA, CyPB and CD147 were reduced to a significantly higher degree after treatment in the observation group. No difference was found in the recurrence rate between the two groups at 6 months after treatment. We conclude that surgery combined with ALA-PDT is a safe and reliable treatment method, which can increase the survival rate while improving the recovery rate and appearance satisfaction in patients with skin cancer.

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Section: Discussionmentioning

confidence: 99%

“…It usually occurs in the exposed parts of the human body, such as the neck, face and upper arm. The most common types are basal cell and squamous cell carcinomas (1). Local invasion by skin cancer cells can cause damage to the local tissues, generating deformations that affect the normal appearance of the patient (2).…”

Section: Introductionmentioning

confidence: 99%

Surgery combined with local 5-aminolevulinic acid-photodynamic therapy on skin cancer and its effect on the expression of cyclophilin A, cyclophilin B and CD147

Guo¹,

Han²

2017

Oncology Letters

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“…Consequently, BCCs of the non-sun-exposed areas, such as axilla, nipple, or the genital and perianal areas are extremely rare. LeSueur et al4 investigated 10,000 BCCs and only 15 axillary BCCs (0.05%) were identified. With regard to the BCCs of the nipple, less than 30 cases were reported in the world5.…”

Section: Discussionmentioning

confidence: 99%

Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas

et al. 2011

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Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.

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“…Le Sueur et al proposed that other covered sites might share the same characteristics. [5] Our case was a noduloulcerative type of BCC but the uncommon location of the lesion and absence of known risk factors (arsenic poisoning, radiation and family history) made the diagnosis challenging. It is not known whether prognosis of a BCC over an uncommon location is any better than those over usual site, but absence of any risk factor is a good prognostic factor.…”

mentioning

confidence: 91%

“…[1] PS is commonest at natal cleft, but it is also reported at various unusual sites like the interdigital clefts of hands and toes, umbilicus, axilla, inter-mammary area, penis, clitoris, scalp, nose, and ear etc. [2][3][4][5] We report first extremely rare case of PS over both eyelids.…”

mentioning

confidence: 99%