Axillary syringomas

An Atlas of Lumps and Bumps: Part 20

“…1 Syringomas are common, benign, sweat gland tumors that originate from the straight intradermal portion of the eccrine sweat duct. 2,3 Histologically, multiple small and dilated eccrine ducts within a dense fibrous stroma are characteristic features. 4 Syringomas usually present during puberty or the third and fourth decades of life.…”

“…4 Syringomas usually present during puberty or the third and fourth decades of life. 3,5 The reported prevalence ranges from 0.6% to 1% of the population. 1,6 The prevalence is higher in Asians and Africans.…”

“…7 The female-to-male ratio is approximately 2:1 in most studies. 3 Most cases occur sporadically, although familial cases have been described. 8 Familial cases may have an autosomal-dominant mode of inheritance.…”

“…5,12 The papules are usually 1 to 3 mm in diameter, asymptomatic, and symmetrically distributed. 3 The lesions may be solitary or, most often, multiple. The distribution may be localized or generalized.…”