Azacycloalkanes

Synthesis of 6,7‐Dihydropyrrolo[2,1‐c][1,3]thiazino[3,2‐a]pyrazine‐4(11bH)‐(thi)ones from 1,2‐Dithiolo‐3‐(thi)ones

“…3H-Benzo[c] [1,2]dithiole-3-thione (1a), [18] 3H- [1,2]dithiolo [3,4-b]pyridine-3-thione (1b), [19] 4-ethyl- [1,2]dithiolo [4,3-b]indole-3(4H)-thione (1c), [20] 3-thioxoindeno-[1,2-c] [1,2]dithiol-4(3H)-one (1d), [21] 5-phenyl-3H-1,2-dithiole-3-thione (1h), [19] 4-phenyl-3H-1,2-dithiole-3-thione (1i), [22] 4-chloro-5-(pyrid-2-ylthio)-3H-1,2-dithiole-3-thione (1j), [23] 4-chloro-5-(phenylthio)-3H-1,2-dithiole-3-thione (1k), [23] 4-chloro-5-phenoxy-3H-1,2dithiole-3-thione (1l), [23] 4-chloro-5-morpholino-3H-1,2-dithiole-3thione (1m), [23] 3,4-dihydropyrrolo[1,2-a]pyrazine (2), [24] 3Hbenzo[c][1,2]-dithiol-3-one (8a), [25] 3H- [1,2]dithiolo [3,4-b]pyridine-3one (8b), [26] 5-phenyl-3H-1,2-dithiole-3-one (8c), [26] (15), [18a] N-methyl-1-phenylmethanimine (17) [27] were prepared according to the published methods and characterized by NMR spectra. The reagents were purchased from commercial sources and used as received.…”