2022
DOI: 10.1186/s12890-022-01985-1
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B cell subsets were associated with prognosis in elderly patients with community acquired pneumonia

Abstract: Background The role of B cell subsets remained to be elucidated in a variety of immune diseases, though which was used as an effective biomarker for anti-inflammatory or antiviral response. This study aimed to evaluate the early changes of B cell subtypes distribution in elderly patients with community acquired pneumonia (CAP), as well as the association between B cell subtypes and prognosis. Methods This prospective study included elderly patients… Show more

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Cited by 2 publications
(2 citation statements)
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“…We hypothesized that LIPO vaccines might elicit protective responses by establishing robust longlived germinal center reactions. To address this, half of the mice were kept under observation for another 6 weeks; then, all of the mice were sacrificed and the memory B cells (IgM + B220 + MHC-II+, Bm) 34 in the spleen or LN were determined. As displayed in Figure 6a−c, both in the spleen and in LNs, more than the double population of the Bm was found compared with the saline group.…”
Section: Pm-lipo Vaccine-mediated Potent Humoral and Cellular Immune ...mentioning
confidence: 99%
“…We hypothesized that LIPO vaccines might elicit protective responses by establishing robust longlived germinal center reactions. To address this, half of the mice were kept under observation for another 6 weeks; then, all of the mice were sacrificed and the memory B cells (IgM + B220 + MHC-II+, Bm) 34 in the spleen or LN were determined. As displayed in Figure 6a−c, both in the spleen and in LNs, more than the double population of the Bm was found compared with the saline group.…”
Section: Pm-lipo Vaccine-mediated Potent Humoral and Cellular Immune ...mentioning
confidence: 99%
“…Thymus preparations can induce the production of macrophages, interferon, interleukin, and other factors, thereby improving the suppressed immune function of the body, and can affect peripheral immune organs to enhance immunity. Fang et al used the thymus method as a neoadjuvant therapy for elderly patients with severe pneumonia, and the results showed that the thymus method can increase the proportion of CD4 and T lymphocyte subsets in vivo [24] . Commonly used thymus preparations are thymosin, thymofaxin, and so on.…”
Section: Immunotherapymentioning
confidence: 99%