Bacillus subtilis Protects the Ducks from Oxidative Stress Induced by Escherichia coli: Efficacy and Molecular Mechanism

Li, Chong; Yang, Li; Li, Shuzhen; Chen, Si; Liu, Guohua; Deng, Xuejuan; Chang, Wenhuan; Cai, Huiyi

doi:10.3390/antiox11101951

Cited by 8 publications

(2 citation statements)

References 67 publications

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“…Recent years have highlighted their benefits in aquaculture, notably in enhancing growth performance, disease control, immune response improvement, and digestive enzyme activity [16,17]. Among these, Bacillus species are widely employed as probiotics in aquatic animals [18][19][20][21]. Studies have demonstrated that probiotics do not lead to drug resistance in aquatic species, making them viable antibiotic substitutes [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Strain-Specific Benefits of Bacillus Probiotics in Hybrid Grouper: Growth Enhancement, Metabolic Health, Immune Modulation, and Vibrio harveyi Resistance

Han,

Song,

Cui

et al. 2024

Animals

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In the realm of modern aquaculture, the utilization of probiotics has gained prominence, primarily due to their ability to enhance growth, boost immunity, and prevent diseases in aquatic species. This study primarily investigates the efficacy of Bacillus subtilis strains, both host-derived and from other sources, in influencing fish growth, immunity, lipid metabolism, and disease resistance. Employing a 42-day feeding trial, we divided hybrid grouper into four distinct groups: a control group on a basal diet and three experimental groups supplemented with 1 × 108 CFU/g of different Bacillus subtilis strains-BS, 6-3-1, and HAINUP40. Remarkably, the study demonstrated that the 6-3-1 and HAINUP40 groups exhibited significant enhancements across key growth parameters: final body weight (FBW), weight gain rate (WGR), feed intake (FI), feed efficiency ratio (FER), and feed conversion ratio (FCR). The investigation into lipid metabolism revealed that the 6-3-1 strain upregulated seven metabolism-related genes, HAINUP40 affected four metabolism-related genes, and the BS strain influenced two metabolism-related genes, indicating diverse metabolic impacts by different strains. Further, a notable reduction in liver enzymes AST and ALT was observed across all supplemented groups, implying improved liver health. Noteworthy was the BS strain’s superior antioxidative capabilities, positively affecting all four measured parameters (CAT, GSH-Px, MDA). In the sphere of immune-related gene expression, the BS strain significantly decreased the expression of both inflammation and apoptosis-related genes, whereas the HAINUP40 strain demonstrated an upregulation in these genes. The challenge test results were particularly telling, showcasing improved survival rates against Vibrio harveyi infection in the BS and 6-3-1 groups, unlike the HAINUP40 group. These outcomes highlight the strain-specific nature of probiotics and their varying mechanisms of action within the host. In conclusion, this study reveals that probiotic strains, varying by source, demonstrate unique, strain-specific effects in promoting growth and modulating immunity in hybrid grouper. This research highlights the promise of tailored probiotic applications in improving aquaculture practices. Such advancements contribute to more sustainable and efficient fish farming methods.

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Section: Introductionmentioning

confidence: 99%

Strain-Specific Benefits of Bacillus Probiotics in Hybrid Grouper: Growth Enhancement, Metabolic Health, Immune Modulation, and Vibrio harveyi Resistance

Han,

Song,

Cui

et al. 2024

Animals

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“…It secretes exogenous digestive enzymes (Abd El-Moneim and Sabic, 2019), which can improve nutrient digestion. Also, it can improve health, performance, ration efficiency, and it can ameliorate the intestinal morphology of ducks (Guo et al, 2016;Zurmiati et al, 2017b;Li et al, 2022;Sun et al, 2022). However, to date there have been no reports concerning the response of male Bayang duck supplemented with a probiotic Bacillus subtilis FNCC 0059.…”

Section: Introductionmentioning

confidence: 99%

Performance Enhancement in Male Bayang Ducks after Oral Administration of the Probiotic Bacillus subtilis FNCC 0059

Zurmiati,

Trisna,

Kurniawan Rusli

et al. 2023

JAHP

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Ducks have a strategic position in Indonesian society, apart from providing quality feed, ducks also offer excellent opportunities to village communities to earn income. However, the high feed conversion of duck is an obstacle in the intensive development of duck farming because 70% of poultry production costs come from feed costs. The purpose of this study was to investigate the effect of Bacillus subtilis FNCC 0059 administration as a probiotic on growing male Bayang duck performance. A randomized design was used in this study. The probiotic Bacillus subtilis FNCC 0059 was included in drinking water of male Bayang ducks at different doses (0, 76x10 6 , 69x10 8 , 65x10 10 , 53x10 12 CFU/ml), and each of these five treatment was replicated four times. Feed intake, body weight gain, feed conversion, and final body weight were the parameters studied. The results revealed that the probiotic Bacillus subtilis FNCC 0059 has a significant (p<0.05) effect on feed intake (being low in 53x10 12 and 65x10 10 CFU/ml), body weight, body weight gain (being high in 69x10 8 , 65x10 10 and 53x10 12 CFU/ml) and feed conversion (being low in 53x10 12 and 65x10 10 CFU/ml) of male Bayang ducks. In conclusion, the administration of probiotic Bacillus subtilis FNCC 0059 in drinking water to male Bayang ducks at a dose of 65x10 10 CFU/ml can improve the performance and feed efficiency of male Bayang ducks.

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Important role of Bacillus subtilis as a probiotic and vaccine carrier in animal health maintenance

Yuan,

Ji,

Zhang

et al. 2024

World J Microbiol Biotechnol

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Bacillus subtilis Protects the Ducks from Oxidative Stress Induced by Escherichia coli: Efficacy and Molecular Mechanism

Cited by 8 publications

References 67 publications

Strain-Specific Benefits of Bacillus Probiotics in Hybrid Grouper: Growth Enhancement, Metabolic Health, Immune Modulation, and Vibrio harveyi Resistance

Strain-Specific Benefits of Bacillus Probiotics in Hybrid Grouper: Growth Enhancement, Metabolic Health, Immune Modulation, and Vibrio harveyi Resistance

Performance Enhancement in Male Bayang Ducks after Oral Administration of the Probiotic Bacillus subtilis FNCC 0059

Important role of Bacillus subtilis as a probiotic and vaccine carrier in animal health maintenance

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