Background Many studies worldwide describe midwives' experiences during their transition from student midwife to qualified midwife. However, research on midwives' experience of transition to practice in the Republic of Ireland has not been published since 2008. This study aimed to explore midwives' experiences of their transition to practice in the Republic of Ireland. Methods A qualitative descriptive study using semi-structured interviews was conducted with seven midwives, who commenced their post-registration clinical practice between December 2018 and September 2019. Results Midwives described transition to practice as a time when they felt challenged because of increased responsibility and accountability. It was a period of growth because of ‘learning by doing’, where a supportive working environment was paramount. Conclusions Newly qualified midwives have considerable need for support yet it appears they do not always receive this support.