Bacteremic skin and soft tissue infection caused by Prevotella loescheii

Mehmood, Mansoor; Jaffar, Nabil A; Nazim, Muhammad; Khasawneh, Faisal A

doi:10.1186/1471-2334-14-162

Cited by 20 publications

(13 citation statements)

References 18 publications

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“…G. intestinalis infection is associated with an enrichment of potentially harmful bacteria ( Figure 8 ) such as Prevotella and A. succiniproducens that have been reported as opportunistic pathogens [ 83 , 84 , 85 ] and genera Megamonas and Catenibacterium , associated with abdominal pain and aggressive behavioral disorder in dogs [ 86 , 87 ].…”

Section: Discussionmentioning

confidence: 99%

Age and Giardia intestinalis Infection Impact Canine Gut Microbiota

et al. 2021

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Giardia intestinalis is a flagellated protozoan responsible for giardiosis (also called giardiasis in humans), the most prevalent and widespread parasitic infection in humans and mammals worldwide. The intestinal microbiota is highly diverse and any alteration in its composition may impact on the health of the host. While studies on the mouse model of giardiosis described the role of the gut microbiota in host susceptibility to infection by the parasite, little is known about the gut microbiota during natural infections in dogs and particularly in puppies. In this study, we monitored naturally G. intestinalis-infected puppies for 3 months and quantified cyst excretion every 2 weeks. All puppies remained subclinically infected during the sampling period as confirmed by fecal examination. In parallel, we performed 16S Illumina sequencing of fecal samples from the different time points to assess the impact of G. intestinalis infection on gut microbiota development of the puppies, as well as gut health markers of immunity such as fecal IgA and calprotectin. Sequencing results revealed that the canine fecal microbiota of Giardia-infected puppies becomes more complex and less diverse with increasing age. In addition, significant differences in the structure of the microbiota were observed between puppies with high and low Giardia cyst excretion. Chronic subclinical G. intestinalis infection appears to be associated with some detrimental structural changes in the gut microbiota. G. intestinalis-associated dysbiosis is characterized by an enrichment of facultative anaerobic, mucus-degrading, pro-inflammatory species and opportunistic pathogens, as well as a reduction of Lactobacillus johnsonii at specific time points. Calprotectin levels increased with age, suggesting the establishment of chronic low-grade inflammation in puppies. Further work is needed to demonstrate whether these alterations in the canine gut microbiota could lead to a dysbiosis-related disease, such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD).

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Section: Discussionmentioning

confidence: 99%

Age and Giardia intestinalis Infection Impact Canine Gut Microbiota

et al. 2021

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“…We identified several potential pathogens as more abundant in livestock workers’ nares and oropharynx in our population. Potential pathogens found in higher abundance in male livestock workers were Prevotella [ 32 – 34 ], Streptococcus [ 35 – 37 ], Moraxella [ 38 , 39 ], Rothia [ 40 ], and Oscillibacter [ 41 ]. While the Oscillbacter , Moraxella , Lactobacillus , Prevotella , Streptococcus , and Rothia genera were observed in the negative control samples, they were not the same OTUs identified by the DESeq2 analysis.…”

Section: Discussionmentioning

confidence: 99%

The nasal and oropharyngeal microbiomes of healthy livestock workers

et al. 2019

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Little information exists on the microbiomes of livestock workers. A cross-sectional, epidemiological study was conducted enrolling 59 participants (26 of which had livestock contact) in Iowa. Participants were enrolled in one of four ways: from an existing prospective cohort study (n = 38), from the Iowa Department of Natural Resources Animal Feeding Operations database (n = 17), through Iowa county fairs (n = 3), and through snowball sampling (n = 1). We collected swabs from the nares and oropharynx of each participant to assess the microbiome via 16s rRNA sequencing. We observed livestock workers to have greater diversity in their microbiomes compared to those with no livestock contact. In the nares, there were 27 operational taxonomic units found to be different between livestock workers and non-livestock workers with the greatest difference seen with Streptococcus and Proteobacteria. In the oropharynx, livestock workers with swine exposure were more likely to carry several pathogenic organisms. The results of this study are the first to characterize the livestock worker nasal and oropharyngeal microbiomes.

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“…acute dental abscess), the central nervous system (e.g. brain abscess), as well as the skin (soft tissue abscess) (Le Moal et al, 2003;Mehmood et al, 2014;Robertson & Smith, 2009). …”

mentioning

confidence: 99%

Prevotella colorans sp. nov., isolated from a human wound

Buhl

Willmann

Liese

et al. 2016

International Journal of Systematic and Evolutionary Microbiology

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A strain of obligately anaerobic, Gram-stain-negative and non-spore-forming rod-shaped bacterium was isolated from a human wound and characterized both phenotypically and genotypically. The strain was moderately saccharolytic and proteolytic. Phylogenetic analysis was based on full-length 16S rRNA gene sequence analysis and revealed the strain to represent a member of the genus Prevotella, but to be different from the described species, with the closest relationship to Prevotella bergensis and Prevotella multisaccharivorax. The genomic DNA G+C content was 43.2 mol%. The most abundant cellular long-chain fatty acids were 3-OH iso-C 17 : 0 , anteiso-C 15 : 0 and iso-C 15 : 0 . In view of phenotypical and biochemical characteristics as well as gene sequencing, strain A1336T is considered to represent a novel species within the genus

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Bacteremic skin and soft tissue infection caused by Prevotella loescheii

Cited by 20 publications

References 18 publications

Age and Giardia intestinalis Infection Impact Canine Gut Microbiota

Age and Giardia intestinalis Infection Impact Canine Gut Microbiota

The nasal and oropharyngeal microbiomes of healthy livestock workers

Prevotella colorans sp. nov., isolated from a human wound

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