Bacterial cellulose based composites enhanced transdermal drug targeting for breast cancer treatment

Zhang, Lingkun; Du, Shiwei; Wang, Xiaozhen; Jiao, Yuxuan; Yin, Liang; Zhang, Yi; Guan, Yan‐Qing

doi:10.1016/j.cej.2019.03.216

Cited by 59 publications

(30 citation statements)

References 55 publications

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“…Recently, BC-based materials have been used in cancer treatment applications. Zhang et al developed BC scaffolds with laser-sensitized magnetic nanoparticles (LMNs) for breast cancer treatment [ 139 ]. For effective treatment, doxorubicin and hematoporphyrin monomethyl ether were dually coated on Fe 3 O 4 magnetic nanoparticles.…”

Section: Applicationsmentioning

confidence: 99%

“… Schematic representation of ( A ) IBU drug release from nf-BC–SA scaffold at different pH conditions, ( B ) under electric field, and ( C ) schematic representation and digital photographs of in vivo efficacy of LMNs treated with tumor-bearing mice by five groups (CK (NS), LMNs, LMNs + M + L, and BC–LMNs + M + L). Reprinted with permission [ 138 , 139 ]. Copyright 2014 Royal Society of Chemistry and 2019 Elsevier.…”

Section: Figurementioning

confidence: 99%

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Bacterial Cellulose and Its Applications

et al. 2022

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The sharp increase in the use of cellulose seems to be in increasing demand in wood; much more research related to sustainable or alternative materials is necessary as a lot of the arable land and natural resources use is unsustainable. In accordance, attention has focused on bacterial cellulose as a new functional material. It possesses a three-dimensional, gelatinous structure consisting of cellulose with mechanical and thermal properties. Moreover, while a plant-originated cellulose is composed of cellulose, hemi-cellulose, and lignin, bacterial cellulose attributable to the composition of a pure cellulose nanofiber mesh spun is not necessary in the elimination of other components. Moreover, due to its hydrophilic nature caused by binding water, consequently being a hydrogel as well as biocompatibility, it has only not only used in medical fields including artificial skin, cartilage, vessel, and wound dressing, but also in delivery; some products have even been commercialized. In addition, it is widely used in various technologies including food, paper, textile, electronic and electrical applications, and is being considered as a highly versatile green material with tremendous potential. However, many efforts have been conducted for the evolution of novel and sophisticated materials with environmental affinity, which accompany the empowerment and enhancement of specific properties. In this review article, we summarized only industry and research status regarding BC and contemplated its potential in the use of BC.

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Section: Applicationsmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

Bacterial Cellulose and Its Applications

et al. 2022

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“…For examples as can be seen from Figure 3, the treated nanocellulose fibers can display as a drug carrier system due to its great number of OH groups. In this manner, different polysaccharides (including chitin [38], nanocellulose [39] and their by-products) have been investigated as novel polymer-anticancer drug conjugates, owing to the enzymatic degradation of the most polysaccharides through colonic microbial agents [40]. Nanocellulose has recently become popular for researchers in drug delivery vehicles, due to their optimal physicochemical and biological features, and the ability for delivering drugs to different organs [41].…”

Section: Nanocellulose In Drug Delivery Systems and Cancer Treatmentsmentioning

confidence: 99%

Nanocellulose as a Vehicle for Drug Delivery and Efficiency of Anticancer Activity: A Short-Review

Yusefi

Shameli

2021

JRNN

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With the high demand of using nanotechnology, nanocellulose has become popular for different biomedical and anticancer applications. Cellulose, a nature gifted material and the most abundant organic polymer on earth, is systematically reviewed. Details of the mechanical and chemical structure of nanocellulose are explained, starting with preparation methods along with physiochemical properties and pH gradient to incorporate innovative polymeric drug delivery vehicles in anticancer applications. A myriad of research fields has introduced nanocellulose as an intriguing candidate for anticancer drug excipient and carrier in modern cancer therapy. Albeit, innovative nanocellulose-based drug carrier systems will be complicated for their commercial use in pharmacies. Of this, it is required to understand the preparation, properties, and potential drug conjugation of nanocellulose to improve its interactions with human tissues.

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“…33,34 It has been reported that cellulose could enhance transdermal targeting. 35 Many researchers have successfully reported the use of semi-synthetic or modified cellulose for transdermal drug delivery. Use of cellulose acetate as transdermal polymer has been documented.…”

Section: Chitosanmentioning

confidence: 99%

Transdermal Patches: State of the Art

Sharma¹,

Thakur²,

Kaur³

et al. 2020

ijddt

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There is a considerable increase in preference for use of transdermal patches over conventional dosage forms owing to the advantages it possesses over them. Transdermal delivery of drugs has undergone rapid advancements through techniques like electroporation, microneedles, iontophoresis etc. This review is aimed at providing deep insight into transdermal technology and its types. An overview of the present market size of transdermal patches along with future prospects has been discussed. Transdermal products being manufactured by Indian pharmaceuticals also has been presented. Various components of transdermal patches being explored have been elaborated. After studying this review, it could be concluded that there are huge prospects for transdermal systems, and research aimed at the delivery of sparingly soluble drugs needs to be done to overcome limitations.

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Bacterial cellulose based composites enhanced transdermal drug targeting for breast cancer treatment

Cited by 59 publications

References 55 publications

Bacterial Cellulose and Its Applications

Bacterial Cellulose and Its Applications

Nanocellulose as a Vehicle for Drug Delivery and Efficiency of Anticancer Activity: A Short-Review

Transdermal Patches: State of the Art

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