“…However, with the rapid development of the tilapia culture industry, various bacterial diseases frequently outbreak due to intensified culture and high stocking density conditions of intensive farming. Pathogens, such as streptococcosis (Anshary, Kurniawan, Sriwulan, Ramli, & Baxa, ; Verner‐Jeffreys et al., ), edwardsiellosis (Kwon, Nam, Kim, & Kim, ; Park & Jeong, ; Soto, Illanes, Revan, Griffin, & Riofrio, ; Soto et al., ), columnaris disease (Dong, Lafrentz, Pirarat, & Rodkhum, ; Sebastiao, Nomura, Sakabe, & Pilarski, ), francisellosis (Assis, Tavares, Pereira, Figueiredo, & Leal, ; Ortega et al., ; Sebastiao, Pilarski, Kearney, & Soto, ) and motile aeromonas septicaemia (Dong et al., ; Li & Cai, ; Soto‐Rodriguez, Cabanillas‐Ramos, Alcaraz, Gomez‐Gil, & Romalde, ), have resulted in substantial economic losses to the local aquaculture industries.…”