“…In the present collection, Ghosh Roy has discussed about how wide range of diseases like cardiovascular, renal and gastrointestinal disorders to cancers like glioblastoma and neurodegenerative diseases; related to autophagy can be understood in the light of miRNA [47]. Similarly, lncRNA have been implicated in maintaining key chromatin architectural features, leading to regulation of chromatin dynamics including aspects like dosage compensation as in X chromosome inactivation, pluripotency, heterochromatin maintenance [5,14,15,18,40]. In this present issue, Heyt et al [21] have highlighted these aspects with special emphasis and comparison of research findings in various model systems.…”