Bacterial Infections

Abstract

This chapter starts by considering the resident bacterial population of the skin and how this has altered with our growing understanding of the skin microbiome. It then reviews the whole range of bacterial skin infections from primary Gram‐positive infections due to staphylococci and streptococci to the less common infections caused by Gram‐negative and anaerobic bacteria. The cutaneous manifestations of common and rare systemic bacterial infections such as staphylococcal septicaemia and melioidosis are described in practical detail. Using new work on antibiotics, the spread of drug resistance amongst skin bacterial pathogens is reviewed and its relevance clarified in the treatment algorithms. Rickettsial infections are also considered.

Valencene, Nootkatone and Their Liposomal Nanoformulations as Potential Inhibitors of NorA, Tet(K), MsrA, and MepA Efflux Pumps in Staphylococcus aureus Strains

“…aureus is an opportunistic pathogen in humans and mammals, colonizing the skin and nasal mucosa without causing disease in most animals. On the other hand, this pathogen can also cause a vast number of conditions, especially when it encounters wounds and ruptures in the skin, among which the following stand out: folliculitis, impetigo, boils, abscesses, septic cellulitis, osteomyelitis, systemic infections, such as pneumonia, endocarditis, and bacteremia, in addition to other secondary infections, underlying inflammatory diseases such as dermatitis and arthritis [4].…”