Bacterial Vaginosis

Abstract

Bacterial vaginosis is the most common vulvovaginal infection and representsthe 35% of all the infections occurring in women in the reproductive age. Serious forms ofcan induce several complications such as spontaneous preterm labour and preterm birth, latemiscarriage and postpartum endometritis, PID, infertility, vaginal cuff infection and postabortalsepsis. Objective: To compare the efficacy of vaginal metronidazole and vaginal clindamycinin the treatment of bacterial vaginosis. Study Design: Interventional: Quasi experimental study.Setting: Obstetrics outpatient department, Ghurki Trust Teaching Hospital, Lahore. Durationof study: Six months i.e. from 01-01-2009 to 30-06-2009. Results: Mean age of patients wasfound to be 24.33 years. In the 100 patients enrolled, no statistically significant difference wasfound between Clindamycin 2% vaginal cream compared with metronidazole 0.75% vaginalgel using Amsell’s criteria. Metronidazole has a failure rate of 13% while failure rate was 6% inthe clindamycin group. Conclusion: A 3 day regimen of clindamycin 2% vaginal cream wasas effective as 5 day regimen of metronidazole 0.75% vaginal gel in the treatment of bacterialvaginosis.