Bacterial Violacein: Properties, Biosynthesis and Application Prospects

Lyakhovchenko, Nikita; Travkin, V. M.; Senchenkov, V.Yu.; Solyanikova, Inna P.

doi:10.1134/s0003683822060072

Cited by 1 publication

(1 citation statement)

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“…Consequently, it can be assumed that the pigment has a bacteriostatic effect on the growth of the test culture population of C. michiganensis VKM Ac-1402. Previously, it has been reported that violacein has antibiotic activity against a number of bacteria and fungi [30]. Cazoto et al presented the results of a study showing that violacein was effective against Staphylococcus aureus isolates at concentrations ranging from 6.25 (0.021 mg/mL) to 25 µM (0.086 mg/mL), and in the case of test cultures of Escherichia coli there was no effect even at 200 µM (0.69 mg/mL) [31].…”

Section: Evaluation Of the Effect Of Violacein Fraction In Dmso On Th...mentioning

confidence: 99%

Bacteriostatic Activity of Janthinobacterium lividum and Purified Violacein Fraction against Clavibacter michiganensis

Lyakhovchenko,

Efimova,

Seliverstov

et al. 2024

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Clavibacter michiganensis causes plant diseases and is included in the list of microorganisms subject to export control. Janthinobacterium lividum is capable of synthesizing a pigment with antagonistic potential. The purpose of the study was to evaluate the activity of J. lividum VKM B-3705D and the pigment fraction against C. michiganensis VKM Ac-1402. The results of spectrophotometric and nuclear magnetic resonance analysis showed that the pigment synthesized by the J. lividum VKM B-3705D corresponds to violacein. The J. lividum strain demonstrated potential bacteriostatic activity against C. michiganensis VKM Ac-1402 when both strains were co-cultured. Compared to the control (DMSO), the violacein solution suppressed the specific growth of Clavibacter by 57.7%. The mechanism of suppression of the growth of Clavibacter is discussed. One of the ways to suppress the growth of C. michiganensis may be the inhibition of key enzymes. Violacein inhibited the activity of adenosine triphosphatase (ATPase, EC 3.6.1.3) compared to the control (DMSO) by 23.2%. Thus, the current study of the bacteriostatic effect may be a decisive step towards the development of a plant protection product.

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Section: Evaluation Of the Effect Of Violacein Fraction In Dmso On Th...mentioning

confidence: 99%