Bacteriologic Profile and Antimicrobial Resistance of Blood Culture Isolates of Septicemic Patients from Various Intensive Care Units in a Teaching Tertiary Care Institute of Haryana, India

Sangwan, Jyoti; Mane, Pratibha; Vohra, Prakriti; Lathwal, Sumit; Malik, Anjali

doi:10.20546/ijcmas.2016.507.067

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“…Moreover, antimicrobial resistance pattern in gram-positive and negative bacteria was as Amoxicillin (88.7%), ampicillin (95.6%), and cotrimoxazole (86.7%), respectively. 24 Based on abovementioned results, S. aureus and E. coli and other members of Enterobacteriaceae have a main role in the incidence of bloodstream infections in different regions. Additionally, the mentioned findings represent different susceptibility and resistance rates.…”

Section: Discussionmentioning

confidence: 97%

Determination of Antimicrobial Resistance Patterns in Bloodstream Infections-Isolated Bacteria From a University Tertiary Hospital Patients

Hasani

Faezi

Rezaee

et al. 2019

Int J Enteric Pathog

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Background: Bloodstream infections are considered a significant medical concern associated with high morbidity and mortality rates. Therefore, physicians should be guided to use antimicrobial susceptibility patterns in order to select appropriate empiric antimicrobial agents to treat the patients who suffer from bacteremia. Objective: The present study aimed to determine antimicrobial resistance and susceptibility patterns in isolates collected from bloodstream infections. Materials and Methods: To achieve this, a total of 710 bacterial blood culture isolates were collected from Sina hospital, and then susceptibility patterns to a number of antibiotics were analyzed according to Clinical and Laboratory Standards Institute guidelines. Results: The identified isolates included Staphylococcus aureus 14 (20.6%), Escherichia coli 14 (20.6%), Acinetobacter baumannii 12 (17.6%), Pseudomonas aeruginosa 11 (16.2%), Coagulasenegative Staphylococcus 8 (11.8%), Klebsiella pneumoniae 6 (8.8%), and Enterobacter spp. 3 (4.4%). The total resistance rate to co-trimoxazole, ceftriaxone, ceftazidime, cefotaxime, ofloxacin, gentamicin, ciprofloxacin, levofloxacin, amikacin, and imipenem was 44 (64.7%), 42 (61.8%), 39 (57.4%), 38 (55.9%), 35 (51.51%), 32 (47.1%), 31 (45.6%), 25 (36.8%), and 27 (39.7%), respectively. Finally, the susceptibility rate to amikacin and imipenem was 43 (63.2%) and 41 (60.3%), respectively. Conclusion: In general, A. baumannii strains isolated from blood cultures were resistant to most antibiotics and the greatest sensitivity was observed to gentamicin (58.3%) compared to other antibiotics. Therefore, gentamicin was found as the most effective antibiotic for treating bloodstream infections caused by A. baumannii.

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Section: Discussionmentioning

confidence: 97%