Bacteriology of acute periapical abscess in children

Brook, Itzhak; Grimm, Stephen R.; Kielich, Raymond B.

doi:10.1016/s0099-2399(81)80060-x

Cited by 94 publications

(48 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…So, it is not surprising to find that the same types of bacteria, which are found in endodontic or periodontal infections, are also prevalent in these abscesses. The bacterial genera most often isolated are Bacteroides, Fusobacterium, Veiltonetta, Streptococcus, Peptostreptoeoccus and Actinomyees (Sabiston et al, 1976;Aderhold et al, t981;Brook et al, 1981;Oguntebi et al, 1982, Labriola et al, 1983Williams et al, 1983). In this laboratory, the recently described species B. endodontalis is isolated in relatively high frequency from submucous abscesses with an endodontic origin (Van Winkelhoff et al, to be published).…”

Section: Oral Submucous Abscessesmentioning

confidence: 99%

Pathogenic synergy: mixed infections in the oral cavity

Steenbergen

Winkelhoff

Graaff

1984

Antonie van Leeuwenhoek

View full text Add to dashboard Cite

In almost all infections in the oral cavity, mixed populations of bacteria are present. However, recent evidence points to a certain specificity in these infections: Streptococcus mutans is related to caries and black-pigmented Bacteroides species are suspected pathogens in periodontal disease. Periodontal diseases, endodontic infections and submucous abscesses in the oral cavity are probably mixed infections in which anaerobic bacteria together with facultatives or other anaerobes are present. In experimental mixed anaerobic infections black-pigmented Bacteroides strains have been shown to play a key role. Little is known about the pathogenic synergy between the bacteria involved in mixed infections. Important mechanisms could be nutritional interrelationships and interactions with the host defense. Within the group of black-pigmented Bacteroides B. gingivalis seems to be the most virulent species. These bacteria possess a great number of virulence factors, which might be important in the pathogenesis of oral infections.

show abstract

Section: Oral Submucous Abscessesmentioning

confidence: 99%

Pathogenic synergy: mixed infections in the oral cavity

Steenbergen

Winkelhoff

Graaff

1984

Antonie van Leeuwenhoek

View full text Add to dashboard Cite

show abstract

“…However, it has been isolated more frequently and in higher numbers from patients with periodontitis and has been shown to be associated with periodontal destruction, particularly in periodontal sites from disease-active patients [3±5]. P. micros is also a known pathogen in other mixed anaerobic infections of the oral cavity, including endodontic abscesses [6,7], periodontal abscesses [8] and peritonsillar infections [9]. It is also often involved in severe mixed anaerobic infections throughout the human body.…”

Section: Introductionmentioning

confidence: 99%

Detection of Peptostreptococcus micros DNA in clinical samples by PCR

Riggio

Lennon

Smith

2001

Journal of Medical Microbiology

View full text Add to dashboard Cite

Peptostreptococcus micros is a gram-positive anaerobic coccus which, although considered to be a natural commensal of the human oral cavity, is associated with periodontal, endodontal and peritonsillar infections. Identi®cation of the organism has to date relied upon conventional culture methods and biochemical analyses. The purpose of this study was to develop a PCR method for rapid and speci®c identi®cation of this organism in clinical samples. A pair of primers was selected, each of which was speci®c at the 39 end for P. micros DNA; they were used in the PCR assay, resulting in a 1074-bp product. The primers were shown to be speci®c for P. micros DNA as no PCR products were obtained when genomic DNA extracts from a wide range of other Peptostreptococcus species and other oral bacteria were used as templates. The PCR assay was then applied to the identi®cation of P. micros DNA in subgingival plaque samples from adult periodontitis patients and pus samples from subjects with acute dento-alveolar abscesses. Con®rmation of speci®c ampli®cation of P. micros DNA was obtained by digestion of PCR products with the restriction endonuclease RsaI, which gives a unique restriction pro®le for P. micros, and DNA sequencing. Sixty-eight subgingival plaque samples from 18 patients were analysed, of which 19 (28%) were positive for P. micros DNA; the proportion of patients carrying P. micros DNA in at least one sampled site was 11 (61%) of 18. Twenty (71%) of 28 pus samples analysed by PCR contained P. micros DNA. These results con®rm that P. micros may be involved in the aetiology of acute dentoalveolar abscesses and adult periodontitis. The PCR assay provides a more rapid and reliable alternative to conventional methods for identi®cation of P. micros in clinical samples.

show abstract

“…These include pulpitis, endodontal and periodontal (gingivitis and periodontitis) infections, periapical and dental abscesses, and perimandibular space infection [14,15]. Pulpitis may progress to form an abscess and eventually involve the mandible and deep neck spaces.…”

Section: Dental Infectionsmentioning

confidence: 99%

The role of anaerobic bacteria in upper respiratory tract and other head and neck infections

Brook

2007

Curr Infect Dis Rep

Self Cite

View full text Add to dashboard Cite

Anaerobes are common pathogens in chronic upper respiratory tract and head and neck infections. They can be recovered in chronic otitis media and sinusitis, play a role in tonsillitis, and predominate in complications of these infections, causing deep oral and neck infections and abscesses. In addition to their direct pathogenicity, they play an indirect role through the production of the enzyme beta-lactamase, "shielding" non-beta-lactamase-producing bacteria from penicillins. Failure to provide adequate therapy against anaerobes may lead to clinical failures. Management of anaerobic infection is complicated by the slow growth of these organisms, by their polymicrobial nature, and by their growing resistance to antimicrobials. Antimicrobials are often the only form of therapy needed, but surgical approach is needed in some cases. Because anaerobes often are mixed with aerobic organisms, the antimicrobials given should provide adequate coverage against all pathogens.

show abstract

Bacteriology of acute periapical abscess in children

Cited by 94 publications

References 5 publications

Pathogenic synergy: mixed infections in the oral cavity

Pathogenic synergy: mixed infections in the oral cavity

Detection of Peptostreptococcus micros DNA in clinical samples by PCR

The role of anaerobic bacteria in upper respiratory tract and other head and neck infections

Contact Info

Product

Resources

About