Balancing Speed and Safety: The Authorisation of Covid-19 Vaccines and Medicines

Stratford, Jemima; MacKenzie, Emily; Mockford, Emma

doi:10.1080/10854681.2020.1780664

Cited by 5 publications

(4 citation statements)

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“…Según los artículos revisados, se evidenciaron investigaciones sobre el efecto de las diversas vacunas anti-COVID-19 catalogados por grupos prioritarios, el mayor porcentaje concentro sus valoraciones en adultos con edades comprendidas entre 27 y 59 años con 35,64%, seguidos por niños entre 6 y 11 años con 31,03%, luego embarazadas 17,24%, mientras que adultos mayores (≥ 60 años) 12,64%; en menor proporción estudios en niños (0-5 años) y jóvenes (12-18 años) 2,30% y 1,15% respectivamente (Tabla 4). Akarsu et al, 2020;Antonelli et al, 2022;Azkur et al, 2020;Calvo et al, 2020;Chauhan et al, 2020;Cooper et al, 2021;Dinleyici et al, 2021;Espejo et al, 2020;Filtenborg et al, 2020;Han et al, 2021;Hodgson et al, 2021;Jeyanathan et al, 2020;Kerboua et al, 2020;Kilic et al, 2021;Krammer et al, 2020;Kyriakidis et al, 2021;Lai et al, 2021;Park et al, 2021;Poland et al, 2020;Sadarangani et al, 2021;Sauré et al, 2021;Shrotri et al, 2021;Kaur & Gupta., 2020;Soiza et al, 2020;Soleimanpour et al, 2021;Stratford et al, 2020;Tregoning et al, 2020;Tregoning et al, 2021;Zheng et al, 2020. 31 (35,64) Niños (6-11 años) Akarsu et al, 2020;Azkur et al, 2020;Calvo et al, 2020;Chen et al, 2020;Cooper et al, 2021;Dinleyici et al, 2021;Fanga et al, 2020;Filtenborg et al, 2020;Goncu Ayhan et al, 2021;…”

Section: Grupos Prioritariosunclassified

Efectividad de las vacunas COVID-19

Castañeda-Rodriguez

Gamboa-Cruzado

Montero

et al. 2022

BMSA

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La pandemia del SARS-CoV-2, ha generado que se realicen esfuerzos considerables en el desarrollo de las vacunas, para comprobar su efectividad se requiere que ensayos clínicos y emplearlos en la población a nivel mundial. Se realizó una revisión sistemática de literatura (RSL) del COVID-19 y su impacto en el desarrollo de las vacunas desde el 2019 hasta el 2022. La estrategia de búsqueda consiguió obtener 8 646 artículos, escogidos de las 6 fuentes de investigación (Wiley Online Library, Taylor & Francis, THE LANCET Infectious Diseases, National Library of Medicine, Nature Portfolio y Oxford Academic), luego se realizó un filtrado de 4 etapas con 2 criterios de exclusión cada una de ellas, quedando solo 78 artículos, los cuáles se utilizaron para responder tres preguntas de investigación planteadas. Se identificaron en los artículos científicos analizados, los laboratorios más referenciados que desarrollaron vacunas Pfizer/ BioNTech, Moderna, AstraZeneca, Sinovac, Sinopharm y Sputnik V, se identificó la utilización de nanotecnología en el diseño de las vacunas, principalmente utilizaron ARN mensajero, vector viral y subunidades proteicas, según el caso con coadyuvantes que potencia la inmunogenicidad. Los estudios demostraron buena efectivad, en los diferentes grupos priorizados y gracias a la dosificación de las inmunizaciones contra la COVID-19, se ha prevenido el número de casos graves y por ende la tasa de mortalidad. Sin embargo, se recomienda promoción y educación sanitaria a la población en general para incentivar la aceptación.

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Section: Grupos Prioritariosunclassified

Efectividad de las vacunas COVID-19

Castañeda-Rodriguez

Gamboa-Cruzado

Montero

et al. 2022

BMSA

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“…The lifesaving impact of vaccination is again being brought into global focus, as it has become the primary preventive and containment measure available for the COVID-19 pandemic [1,2]. Prior to the outbreak of the pandemic, vaccination, which is an acclaimed successful public health intervention, was faced with various challenges.…”

Section: Introduction 1backgroundmentioning

confidence: 99%

Overview of Tools and Measures Investigating Vaccine Hesitancy in a Ten Year Period: A Scoping Review

et al. 2022

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The challenge of vaccine hesitancy, a growing global concern in the last decade, has been aggravated by the COVID-19 pandemic. The need for monitoring vaccine sentiments and early detection of vaccine hesitancy in a population recommended by the WHO calls for the availability of contextually relevant tools and measures. This scoping review covers a ten year-period from 2010–2019 which included the first nine years of the decade of vaccines and aims to give a broad overview of tools and measures, and present a summary of their nature, similarities, and differences. We conducted the review using the framework for scoping reviews by Arksey and O’Malley (2005) and reported it following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews’ guidelines. Of the 26 studies included, only one was conducted in the WHO African Region. Measures for routine childhood vaccines were found to be the most preponderant in the reviewed literature. The need for validated, contextually relevant tools in the WHO Africa Region is essential, and made more so by the scourge of the ongoing pandemic in which vaccination is critical for curtailment.

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“…The emergence of different, more virulent strains of high infectivity, of which there are at least four variants currently circulating in different parts of the world [3][4][5][6], coupled with multiple waves of the pandemic [7][8][9][10], further compound the problem. It has been suggested that in order to effectively contain the menace of the pandemic, population-wide vaccination is crucial [11][12][13]. It is widely acknowledged that the success of any vaccination endeavor depends largely on the healthcare workforce, who usually are the most trusted source of health information for the public [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Estimating Vaccine Confidence Levels among Healthcare Staff and Students of a Tertiary Institution in South Africa

et al. 2021

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Healthcare workers were the first group scheduled to receive COVID-19 vaccines when they became available in South Africa. Therefore, estimating vaccine confidence levels and intention to receive COVID-19 vaccines among healthcare workers ahead of the national vaccination roll-out was imperative. We conducted an online survey from 4 February to 7 March 2021, to assess vaccine sentiments and COVID-19 vaccine intentions among healthcare staff and students at a tertiary institution in South Africa. We enrolled 1015 participants (74.7% female). Among the participants, 89.5% (confidence interval (CI) 87.2–91.4) were willing to accept a COVID-19 vaccine, 95.4% (CI 93.9–96.6) agreed that vaccines are important for them, 95.4% (CI 93.8–96.6) that vaccines are safe, 97.4% (CI 96.2–98.3) that vaccines are effective, and 96.1% (CI 94.6–97.2) that vaccines are compatible with religion. Log binomial regression revealed statistically significant positive associations between COVID-19 vaccine acceptance and the belief that vaccines are safe (relative risk (RR) 32.2, CI 4.67–221.89), effective (RR 21.4, CI 3.16–145.82), important for children (RR 3.5, CI 1.78–6.99), important for self (RR 18.5, CI 4.78–71.12), or compatible with religion (RR 2.2, CI 1.46–3.78). The vaccine confidence levels of the study respondents were highly positive. Nevertheless, this could be further enhanced by targeted interventions.

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Balancing Speed and Safety: The Authorisation of Covid-19 Vaccines and Medicines

Cited by 5 publications

References 0 publications

Efectividad de las vacunas COVID-19

Efectividad de las vacunas COVID-19

Overview of Tools and Measures Investigating Vaccine Hesitancy in a Ten Year Period: A Scoping Review

Estimating Vaccine Confidence Levels among Healthcare Staff and Students of a Tertiary Institution in South Africa

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