Bariatric surgery is associated with reduced admission for aortic dissection: a nationwide case-control analysis

Okida, Luis Felipe; Sasson, Morris; Wolfers, Matthew; Liang, Hong; Balzan, Jorge; Menzo, Emanuele Lo; Szomstein, Samuel; Grove, Mark K.; Navia, José L.; Rosenthal, Raúl J.

doi:10.1016/j.soard.2021.05.015

Cited by 4 publications

(2 citation statements)

References 51 publications

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“…Hyperlipidaemia and obesity are major contributing factors to the occurrence of aortic dissection and other aortic diseases [ 1 , 2 ]. Open surgery is the main method to treat these diseases, including Sun's procedure for aortic dissection and arterial bypass surgery for the treatment of atherosclerosis obliterans [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Reduction of oxidative stress response and protection of liver and renal cell functions by reduced glutathione in lower limb arterial ischemia–reperfusion in New Zealand white rabbits with high triglyceride levels

Wang,

Sun,

Cheng

et al. 2024

Heliyon

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Section: Introductionmentioning

confidence: 99%

Reduction of oxidative stress response and protection of liver and renal cell functions by reduced glutathione in lower limb arterial ischemia–reperfusion in New Zealand white rabbits with high triglyceride levels

Wang,

Sun,

Cheng

et al. 2024

Heliyon

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“…Morbid obesity is relevant to more complications, such as acute lung injury (ALI) and hypoxemia in T(A)AD patients [ 15 ]. Also, bariatric surgery is associated with a lower likelihood of admission for aortic dissection [ 16 ]. Few studies have concentrated specifically on in-hospital outcomes of T(A)AD inpatients with morbid obesity.…”

Section: Introductionmentioning

confidence: 99%

Morbid obesity impacts mortality among inpatients with type a aortic dissection: an analysis of the national inpatient sample

Yin

Zhi

et al. 2023

J Cardiothorac Surg

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Background Stanford type A aortic dissection (T(A)AD) is one of the most dangerous cardiovascular diseases and morbid obesity is associated with the prognosis of many cardiovascular diseases. The aim of this study is to investigate the impact of morbid obesity on in-hospital mortality, total hospital costs and discover the prevalence of morbid obesity among inpatients with T(A)AD. Methods Patients with a primary diagnosis of T(A)AD were identified from the National Inpatient Sample database (NIS) from 2008 to 2017. These patients were categorized into non-obesity, obesity and morbid obesity. Multivariable regression models were utilized to assess the association between obesity/morbid obesity and in-hospital mortality, total cost and other clinical factors. The temporal trend in prevalence of obesity/morbid obesity in T(A)ADs and the trend of in-hospital mortality among different weight categories were also explored. Results From the NIS database 8489 T(A)AD inpatients were identified, of which 7230 (85.2%) patients were non-obese, 822 (9.7%) were obese and 437 (5.1%) were morbid obese. Morbid obesity was associated with increased risk of in-hospital mortality (odds ratio [OR] 1.39; 95% confidence interval [CI] 1.03–1.86), 8% higher total cost compared with the non-obese patients. From 2008 to 2017, the rate of obesity and morbid obesity in patients with T(A)AD have significantly increased from 7.36 to 11.33% (P < 0.001) and from 1.95 to 7.37% (P < 0.001). Factors associated with morbid obesity in T(A)ADs included age, female, elective admission, hospital region, dyslipidemia, smoking, rheumatoid arthritis/collagen vascular diseases, chronic pulmonary disease, diabetes and hypertension. Conclusions Morbid obesity are connected with worse clinical outcomes and more health resource utilization in T(A)AD patients. Appropriate medical resource orientation and weight management education for T(A)AD patients may be necessary.

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The effects of bariatric surgery on cardiovascular diseases

Coşkun

2021

Surgery for Obesity and Related Diseases

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Bariatric surgery is associated with reduced admission for aortic dissection: a nationwide case-control analysis

Cited by 4 publications

References 51 publications

Reduction of oxidative stress response and protection of liver and renal cell functions by reduced glutathione in lower limb arterial ischemia–reperfusion in New Zealand white rabbits with high triglyceride levels

Reduction of oxidative stress response and protection of liver and renal cell functions by reduced glutathione in lower limb arterial ischemia–reperfusion in New Zealand white rabbits with high triglyceride levels

Morbid obesity impacts mortality among inpatients with type a aortic dissection: an analysis of the national inpatient sample

The effects of bariatric surgery on cardiovascular diseases

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