2000
DOI: 10.1152/ajpregu.2000.279.4.r1437
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Baroreflexes prevent neurally induced sodium retention in angiotensin hypertension

Abstract: Recent studies indicate that renal sympathetic nerve activity is chronically suppressed during ANG II hypertension. To determine whether cardiopulmonary reflexes and/or arterial baroreflexes mediate this chronic renal sympathoinhibition, experiments were conducted in conscious dogs subjected to unilateral renal denervation and surgical division of the urinary bladder into hemibladders to allow separate 24-h urine collection from denervated (Den) and innervated (Inn) kidneys. Dogs were studied 1) intact, 2) aft… Show more

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Cited by 88 publications
(123 citation statements)
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References 33 publications
(77 reference statements)
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“…1,12 Standard techniques were used to measure hematocrit and the plasma concentrations of sodium, potassium, and protein. 6 Arterial pressure and heart rate were monitored continuously, 24 h/day, from an arterial catheter.…”
Section: Methodsmentioning
confidence: 99%
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“…1,12 Standard techniques were used to measure hematocrit and the plasma concentrations of sodium, potassium, and protein. 6 Arterial pressure and heart rate were monitored continuously, 24 h/day, from an arterial catheter.…”
Section: Methodsmentioning
confidence: 99%
“…The procedures for renal denervation, implantation of vascular catheters, implantation of stimulating electrodes around each carotid sinus, and the connection of electrode lead bodies to a pulse generator have been described previously. 1,6,12 Also, as described previously, the dogs were maintained in metabolic cages. 1,6 The electrodes and the pulse generator were provided by CVRx, Inc.…”
Section: Animal Preparationmentioning
confidence: 99%
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