Bartonellosis in cats: a role in uveitis?

Stiles, Jean

doi:10.1111/j.1463-5224.2011.00901.x

Cited by 11 publications

(8 citation statements)

References 61 publications

(123 reference statements)

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“…Infectious causes can be further subdivided into protozoal (eg, Toxoplasma gondii) , 2–9 viral (eg, feline leukemia virus, 10 feline immunodeficiency virus), 10–17 bacterial (eg, Bartonella spp . ) 18–20 mutated feline coronavirus causing feline infectious peritonitis (FIP), 21–23 and fungal (eg, cryptococcus) 24–26 . The role of Bartonella spp.…”

Section: Introductionmentioning

confidence: 99%

A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases

Wegg¹,

Jeanes

Pollard

et al. 2021

Veterinary Ophthalmology

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Purpose The purpose of this study was to investigate the most common causes of endogenous feline uveitis in a UK referral population and to investigate associations based on signalment. Methods Retrospective multicenter cross‐sectional study from 2010 to 2019 including cats presented to the Animal Health Trust and the Royal Veterinary College with clinical signs consistent with uveitis. Cats were included in analyzes if they had a full physical examination including an ophthalmic examination, complete blood count, serum biochemistry, and infectious disease testing for at least two diseases unless the diagnosis was found on clinical examination (eg, neoplasia). Results A total of 92 cats were included in the study. The majority of cats presenting with uveitis were male (66.3%). The most common causes of endogenous uveitis were idiopathic uveitis (42/92 45.7%), feline infectious peritonitis (FIP) 15/92 16.3%), and lymphoma (10/92 10.9%). Fisher's exact test showed differences in breed across diagnosis groups (p = .002) with purebred cats being overrepresented in the lymphoma and FIP groups. Kruskal‐Wallis test showed differences in median age across diagnosis groups (p < .001) with cats in the FIP group having the youngest age (median 1.4 years, interquartile range (IQR) 0.4–1.8 years) and cats in the neoplasia (primary or paraneoplastic) group having the oldest age (median 12.8 IQR 10.8–13.8). Idiopathic uveitis was unilateral in 56.1% of cases, and infectious causes were unilateral in 47.8% of cases. Conclusions The most common cause of endogenous uveitis in a population of cats in the UK was idiopathic uveitis, followed by FIP and lymphoma.

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Section: Introductionmentioning

confidence: 99%

A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases

Wegg¹,

Jeanes

Pollard

et al. 2021

Veterinary Ophthalmology

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“…It is of note that the caribou nidovirus sequences were detected in eye swabs of caribou only. The ability of coronaviruses to replicate in the eye has been described previously, where mouse hepatitis virus A59 was shown to induce optic neuritis in an experimental animal model [42,43] and feline coronaviruses were capable of causing uveitis [44]. In addition, the presence of SARS coronavirus in tears has been reported [45].…”

Section: Discussionmentioning

confidence: 86%

Metagenomic Survey for Viruses in Western Arctic Caribou, Alaska, through Iterative Assembly of Taxonomic Units

et al. 2014

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Pathogen surveillance in animals does not provide a sufficient level of vigilance because it is generally confined to surveillance of pathogens with known economic impact in domestic animals and practically nonexistent in wildlife species. As most (re-)emerging viral infections originate from animal sources, it is important to obtain insight into viral pathogens present in the wildlife reservoir from a public health perspective. When monitoring living, free-ranging wildlife for viruses, sample collection can be challenging and availability of nucleic acids isolated from samples is often limited. The development of viral metagenomics platforms allows a more comprehensive inventory of viruses present in wildlife. We report a metagenomic viral survey of the Western Arctic herd of barren ground caribou (Rangifer tarandus granti) in Alaska, USA. The presence of mammalian viruses in eye and nose swabs of 39 free-ranging caribou was investigated by random amplification combined with a metagenomic analysis approach that applied exhaustive iterative assembly of sequencing results to define taxonomic units of each metagenome. Through homology search methods we identified the presence of several mammalian viruses, including different papillomaviruses, a novel parvovirus, polyomavirus, and a virus that potentially represents a member of a novel genus in the family Coronaviridae.

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“…Μεταξύ των άλλων μειονεκτημάτων της καλλιέργειας συγκαταλέγονται ο αυξημένος κίν δυνος επιμολύνσεων, ο μεγάλος χρόνος επώασης (6-8 εβδομάδες) (La Scola et al 2002) και το γεγονός ότι συχνά απαιτούνται περισσότερες από μια καλλιέργειες για την επιτυχή απομόνωση του βακτηρίου (Birtles et al 2002). Ωστόσο, η χρήση νέων ενισχυμένων υγρών θρεπτικών υποστρωμάτων φαίνεται ότι αυξάνει την ευαισθησία της καλλιέργειας ακόμη και με μικρό βακτηριακό φορτίο (Maggi et al 2005) ενώ η τήρηση κανόνων αντισηψίας αποτρέπει την επιμόλυνση του δείγματος κατά την αιμοληψία από το δέρμα στο οποίο ενδέχεται να υπάρχουν περιττώματα μολυσμένου ψύλ λου (Stiles 2011).…”

Section: κλινικη εικονα κλι εργαστηριακα ευρηματαunclassified

Feline bartonellosis· A review

Athanasiou¹,

Chatzis²,

Κοντου)

et al. 2017

J Hellenic Vet Med Soc

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ABSTRACT, Bartonella infection is caused by Gram negative bacteria commonly isolated from domestic cats. Cats are the major reservoir of Bartonella henselae, B> clarridgeiae and B. koehlerae which are transmitted to humans, while they are accidental host of B, quintana. Β, bovis και Β, vìmonìi subsp. berkhoffìi. The pathogen is transmitted among cats mainly by fleas while other vectors are also suspicious for transmission since the bacteria have been isolated from ticks and flies. The bacterial pathogenicity may be emphasized by the strain of the bacterium and the immune status of the infected host Most of the infected eats remain asymptomatic. In the natural occurring cases of feline bartonellosis uveitis, chronic gingivostomatitis and endocarditis have been reported. Mild anemia and leucocitosi s in the early phase of the infection has been also reported. Diagnosis is based on the detection of the specific anti-bartoneila antibodies by the inderict immunofluorescent test, ELISA and Western blot assays. Molecular biology techniques mainly PCR, cytology, histopathology and blood culture have also been employed for the direct detection of the pathogen. Prolonged antimicrobial therapy results to the reduction of bacterial burden without total elimination of the pathogen.Bartonella henselae is the causative agent of cat scratch disease, a human infection usually characterized by persistent regional lymphadenopathy and less frequently fever while angiomatosis or hepatic peliosis have been reported mainly in immunocompromised patients. It is transmitted to humans by cat scratches or bites. The most effective means of protection is regular flea control Additionally, commonsense precautions and hygiene such as washing hands after handling pets and clean any cats and bites or scratches promptly are recommended especially in population at great risk.

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Bartonellosis in cats: a role in uveitis?

Cited by 11 publications

References 61 publications

A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases

A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases

Metagenomic Survey for Viruses in Western Arctic Caribou, Alaska, through Iterative Assembly of Taxonomic Units

Feline bartonellosis· A review

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