Basal Cell Carcinoma

Basal Cell Carcinoma

“…BCC located in embryonic fusion planes, periauricular region, tends to be at high risk of deep extension. It has been shown that the highest risk tumors which exhibit extensive subclinical spread are basosquamous and morpheaform BCC found on nose and morpheaform BCC on cheek and those with a preoperative size greater than 25 mm (Batra, 2002& Schwartz, 2008. The tendency of BCC to spread into the dermis is understandable, because it develops immediately beneath the epidermis.…”

“…The surrounding stroma showing myxoid change, is rarely fibrotic and may show calcification in discrete islands of tumour or in adjacent stroma. This subtype of BCC grows slowly; however if left untreated for enough time, it can invade structures and increase morbidity (Miller, 2008;Nouri, 2007& Schwartz, 2008. According to some authors multinodular BCC is accepted as an another subtype of BCC.…”

“…Local invasion is the most important problem of BCC (Carucci, 2008& Schwartz, 2008. It grows in a "silent" way into immediately adjacent tissue (Figure 7).…”

“…These lesions are usually misdiagnosed, leading to greater tumour growth and delayed treatment. This is an aggressive growth variant of BCC (Mackie, 2004;Nouri, 2007;Schwartz, 2008& Tzellos 2010. In histopathology; there is a fibrotic dermis that contains small, linear, and branching collections of basal cells.…”

“…Mitoses are infrequent, and apoptotic cells are rare in the atypical basaloid buds. When seen in the setting of a biopsy for suspect superficial BCC, a band-like lymphoid infiltrate should prompt a careful search through multipl levels looking for foci of superficial BCC (Nouri, 2007;Schwartz, 2008& Tzellos 2010). In dermoscopy; according to a study, shiny white to red areas were seen in 100% of the lesions, while approximately 86% revealed short fine telangiectasias; they also described small surface ulcerations or erosions in about 78% of the lesions.…”