Basaloid squamous cell carcinoma

Poornima, Vinaya; Patankar, Sangeeta; Sridharan, Gokul; Khot, Komal

doi:10.4103/0973-029x.92997

Cited by 12 publications

(13 citation statements)

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“…Differential diagnosis for BSCC includes basal cell carcinoma, adenoid cystic carcinoma (solid variant), adenosquamous carcinoma, basal cell adenocarcinoma, salivary duct carcinoma and neuroendocrine carcinoma. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

“…Mucin is present in the surrounding stroma, with cleft artifact occurring between tumor nests and surrounding stroma. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

“…Adenoid cystic carcinoma (ACC, solid variant) shows groups of cuboidal cells, with dark nuclei. [ 10 ] ACC lacks areas of squamous differentiation, cytologic and nuclear atypia; antibodies to CD117 react with most ACCs. [ 11 ] To differentiate BSCC from ACC (solid variant) we have applied CD117 because ACCs are positive for CD117 whereas BSCCs are not.…”

Section: Discussionmentioning

confidence: 99%

“…For the diagnosis of carcinoma, there should be more than 4-5 mitotic figures per 10 high-power fields. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

“…Salivary duct carcinoma shows tumor islands with large central cystic spaces with comedo necrosis and a several cell layers-thick peripheral tumor cells that are cuboidal/polygonal and have a moderate amount of eosinophilic cytoplasm. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

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Basaloid squamous cell carcimoma: A rare case report with review of literature

Shivakumar

Dash

Sahu

et al. 2014

J Oral Maxillofac Pathol

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Basaloid squamous cell carcinoma (BSCC) is a distinct variant of conventional squamous cell carcinoma (SCC), predominantly localized in the upper aerodigestive tract. In the head and neck region, the tumor has a strong predilection for extra-laryngeal sites, such as the base of the tongue, tonsil, hypopharynx and supraglottic larynx. BSCC has well-defined histological features, characterized by nesting, lobular and trabecular arrangement of basaloid cells. Central comedonecrosis within the cell nests, cells with nuclear palisading and high-grade dysplasia in overlying mucosa are the main characteristics. The tumor is considered to be highly aggressive and often presents itself as an advanced stage lesion, thus demanding early diagnosis and prompt treatment. We here report a case of 72-year-old male diagnosed with BSCC involving the right tonsillar region.

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Section: Discussionmentioning

confidence: 99%

“…Mucin is present in the surrounding stroma, with cleft artifact occurring between tumor nests and surrounding stroma. [ 10 ]…”

Section: Discussionmentioning

confidence: 99%