Baseline Anterior Segment Parameters Associated with the Long-term Outcome of Laser Peripheral Iridotomy

Abstract

Thin peripheral iris and less AOD750 at baseline were associated with greater changes in longitudinal assessment after LPI. PACS eyes with thick peripheral iris at baseline showed less AOD750 change at both early and late follow up after LPI; therefore, such eyes should be followed with caution despite successful LPI.

Role of anterior segment optical coherence tomography in angle‐closure disease: a review

“…72 An unsuccessful LPI outcome (two or more quadrants closed after LPI) or less AOD750 change was associated with pre-laser greater angle closure 64,65,67 , less anterior iris bowing in light conditions 64,65 and thick peripheral iris at baseline. 73 For those eyes that remain gonioscopically closed after LPI, argon laser peripheral iridoplasty (ALPI) increased all angle parameters measured by SS-OCT and maintained a non-occludable gonioscopic configuration for 6 weeks following treatment. 74 Furthermore, ALPI seemed to increase all angle parameters by AS-OCT in APAC eyes when compared with medical treatment.…”

Clinical and Anterior Segment Anatomical Features in Primary Angle Closure Subgroups Based on Configurations of Iris Root Insertion

“…When both eyes were included, all participants showed a concordant iris insertion shape in the right and left eyes. There is growing evidence that the iris plays an important role in the pathogenesis of angle closure glaucoma [ 11 12 13 ]. In the past, it was not possible to visualize the entire shape of the iris configuration, including the iris cross-sectional area or IT at various locations, or the position of the iris root insertion into the ciliary body.…”

“…Wang et al [ 10 11 ] reported that iris curvature (IC), iris area (IA), and iris thickness (IT) were independently associated with a narrow angle. In addition, peripheral IT was recently reported as an important predictor of the outcome of laser peripheral iridotomy [ 12 13 ]. Another interesting point is the location of the iris root insertion into the ciliary body.…”

Anterior segment imaging in glaucoma: An updated review

“…[ 17 ] Other biometric parameters that can be measured by the AS-OCT include: Iris thickness, iris curvature, AC depth, AC width, and lens vault. [ 18 ] These parameters are further described in Table 2 . Difficulty in identifying the scleral spur as a reference point has been cited in numerous prior studies, with a rate of 15–28% of AS-OCT images unable to identify the scleral spur.…”